The morphological aspect of the carotid pulse has been under study in 47 cases of juxtavalvular aortic stenosis previously confirmed through hemodynamic and surgical examinations. The study included 39 cases of subvalvular fibrous stenosis (subaortic fibrous stenosis) (SAsV) and 8 cases of supravalvular annular aortic stenosis (S AsV). In 75% of both SAsV and SAsV cases the carotid pulse showed a rapid ascent and a finely notched apex, while in 25% of the cases it followed the pattern of a typical valvular stenosis. This is more obvious for the left carotid artery. The morphology of the carotid pulse resulted as independent from the aortic ventricular gradient, but, on the other hand, connected with the simultaneous stenotic involvement of the valvular cusps. The sign possesses not only high sensitivity but also high specificity with regard to juxtavalvular aortic stenoses because it has only been met with in 2 cases of valvular aortic stenosis. The pathophysiological explanation remains as yet obscure.
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JACC Case Rep
January 2025
Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
A 51-year-old man with a history of antibiotic therapy for syphilis 1 month ago presented with syncope. Computed tomography revealed circumferential aortic wall thickening complicating severe stenosis of left main coronary ostium. Abnormalities in serologic and cerebrospinal fluid tests led to the diagnosis of syphilitic aortitis and neurosyphilis.
View Article and Find Full Text PDFJACC Case Rep
January 2025
Interventional Cardiology Section, Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Aneurysms of the interventricular membranous septum are a rare anatomical feature that can be detected incidentally on computed tomography or echocardiography. Such aneurysms can pose challenges in the treatment of patients with aortic valve stenosis. A case series of 2 patients with membranous septal aneurysms treated successfully with current-generation balloon-expandable and self-expanding transcatheter heart valves is presented here.
View Article and Find Full Text PDFAm J Transl Res
December 2024
Department of Cardiac Surgery, The Second Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
Objective: To identify the risk factors associated with moderate to severe perivalvular leakage (PVL) after transcatheter aortic valve replacement (TAVR) and to construct a prediction model for this risk.
Methods: A retrospective analysis was conducted on 128 patients with severe aortic stenosis who had received TAVR in The Second Hospital of Hebei Medical University from January 2019 to January 2024. The length of the aortic regurgitation bundle and annular circumference ratio were measured by transesophageal echocardiography immediately after the valve implantation.
Acta Physiol (Oxf)
February 2025
PhyMedExp, IPAM/Biocampus, University of Montpellier, INSERM, CNRS., Montpellier, France.
Aim: Left atrial (LA) strain is emerging as a valuable metric for evaluating cardiac function, particularly under pathological conditions such as pressure overload. This preclinical study investigates the predictive utility of LA strain on cardiac function in a murine model subjected to pressure overload, mimicking pathologies such as hypertension and aortic stenosis.
Methods: High-resolution ultrasound was performed in a cohort of mice (n = 16) to evaluate left atrial and left ventricular function at baseline and 2 and 4 weeks after transverse aortic constriction (TAC).
Kardiol Pol
January 2025
Department of Cardiology and Cardiovascular Interventions, University Hospital, Kraków, Poland.
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