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Sleep quality in individuals with post-COVID-19 condition: Relation with emotional, cognitive and functional variables.
Brain Behav Immun Health
February 2024
Clinical Research Group for Brain, Cognition and Behavior, Consorci Sanitari de Terrassa, Terrassa, Spain.
The study aimed to assess sleep quality in PCC patients and its predictors by analysing its relationship with emotional, cognitive and functional variables, as well as possible differences based on COVID-19 severity. We included 368 individuals with PCC and 123 healthy controls (HCs) from the NAUTILUS Project (NCT05307549 and NCT05307575). We assessed sleep quality (Pittsburgh Sleep Quality Index, PSQI), anxiety (Generalized Anxiety Disorder, GAD-7), depression (Patient Health Questionnaire, PHQ-9), global cognition (Montreal Cognitive Assessment, MoCA), everyday memory failures (Memory Failures of Everyday Questionnaire, MFE-30), fatigue (Chadler Fatigue Questionnaire, CFQ), quality of life (European Quality of Life-5 Dimensions, EQ-5D), and physical activity levels (International Physical Activity Questionnaire, IPAQ).
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- The study explored associations between risk factors and colorectal cancer in Lleida, Spain, using data from 1083 cancer episodes from 2012 to 2015.
- It employed multiple correspondence analysis (MCA) and k-means clustering to identify patient groups with similar risk factors, revealing that older age and obesity increased mortality risk.
- Findings indicated MCA and k-means are effective for uncovering links between risk factors and patient characteristics, supporting their use in cancer research.
Metabolomic Analysis Points to Bioactive Lipid Species and Acireductone Dioxygenase 1 (ADI1) as Potential Therapeutic Targets in Poor Prognosis Endometrial Cancer.
Cancers (Basel)
June 2022
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Monforte de Lemos 3-5, 28029 Madrid, Spain.
Metabolomic profiling analysis has the potential to highlight new molecules and cellular pathways that may serve as potential therapeutic targets for disease treatment. In this study, we used an LC-MS/MS platform to define, for the first time, the specific metabolomic signature of uterine serous carcinoma (SC), a relatively rare and aggressive variant of endometrial cancer (EC) responsible for 40% of all endometrial cancer-related deaths. A metabolomic analysis of 31 ECs (20 endometrial endometrioid carcinomas (EECs) and 11 SCs) was performed.
View Article and Find Full Text PDFUmbilical incisional hernias (M3): are trocar-site hernias different? Comparative analysis of the EVEREG registry⋆.
Cir Esp (Engl Ed)
June 2022
Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain; Servicio de Cirugía General, Hospital Universitari del Mar, Barcelona, Spain. Electronic address:
Background: Incisional hernia (HI), in open and laparoscopic surgery, is a very frequent complication. HI located in the umbilical region are called M3. The main aim of this study is to compare HI produced by the placement of an umbilical laparoscopic trocar (M3T) with those located in M3 in open surgery (M3O) in terms of basal characteristics, complications and recurrences; and secondarily the identification of risk factors.
View Article and Find Full Text PDFAssessment of incidence and trends in cerebrovascular disease in the healthcare district of Lleida (Spain) in the period 2010-2014.
Neurologia (Engl Ed)
October 2022
Grupo de Neurociencias Clínicas, Universidad de Lleida, IRBLleida, Lleida, Spain; Unidad de Ictus, Hospital Universitario Arnau de Vilanova, Lleida, Spain. Electronic address:
Objectives: This study aimed to determine the incidence and trends of cerebrovascular disease (CVD) in the healthcare district of Lleida.
Material And Methods: We performed a population-based prospective cohort study including the entire population of the healthcare district of Lleida (440 000 people). Information was gathered from the minimum basic data set from the emergency department and hospital discharges for the period from January 2010 to December 2014.
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