Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1099/00221287-53-3-341 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Thyroid function, autoimmunity, thyroid volume, and metabolic profile in people with Hashimoto thyroiditis.
BMC Endocr Disord
December 2024
Basic and Clinical Immunology, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.
Background: Hashimoto's thyroiditis (HT) is associated with high cardiovascular risk. Thyroid volume has a notable dispersion of values in these patients. This study aims to clarify the association between thyroid antibodies, thyroid morphology, insulin resistance, and lipid profile in patients with HT.
View Article and Find Full Text PDFUnderstanding lipidomics associations and the lipoprotein-related caveats in population epidemiology.
Am J Epidemiol
November 2024
Systems Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Mass spectrometry lipidomics is becoming customary to analyse serum/plasma samples in epidemiology. The measurables are molecular constituents of lipoprotein particles, but very little is known on the consequences of adjusting lipidomics data with lipoprotein measures. We studied two population cohorts with 5,657 and 2,036 participants.
View Article and Find Full Text PDFNew aspect on the regulation of in vitro oocyte maturation: role of the obesity, neuropeptides and adipokines.
J Assist Reprod Genet
December 2024
Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Krakow, 30-387, Krakow, Poland.
Oocyte quality determinants and nuclear and cytoplasmic maturation establish essential processes for fertilization and further development of the conceptus. Moreover, female fertility is strongly dependent on the metabolic status of the organism. Numerous sources indicate that obesity impairs ovarian function including oocyte physiology by inhibiting nuclear maturation, stimulating lipotoxicity and inflammation, enabling cumulus cells apoptosis, promoting reactive oxygen species formation and ultimately imposing pathogenic effects on mitochondria leading to infertility.
View Article and Find Full Text PDFChronic Gastroesophageal Reflux Dysregulates Proteostasis in Esophageal Epithelial Cells.
Cell Mol Gastroenterol Hepatol
December 2024
Department of Surgery, University of Miami, Miami, Florida; Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida; Department of Veterans Affairs, Miami VA Healthcare System, Miami, Florida. Electronic address:
Article Synopsis
- GERD is a common digestive disorder that causes damage to the esophagus due to stomach acid exposure, which can lead to serious complications like esophageal tumors and is characterized by oxidative stress and reactive byproducts known as isoLGs.
- The study examined how isoLGs interact with and cause misfolding and aggregation of proteins, using various assays and animal models to analyze esophageal tissues affected by GERD.
- The findings reveal that GERD leads to protein misfolding and cell death through mechanisms involving isoLG adduction, suggesting it shares features with other diseases related to protein aggregation.
From adiposity to steatosis: metabolic dysfunction-associated steatotic liver disease, a hepatic expression of metabolic syndrome - current insights and future directions.
Clin Diabetes Endocrinol
December 2024
Department of Nursing, Central Washington College, Enugu, Nigeria.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing health concern and the risk of its development is connected with the increasing prevalence of metabolic syndrome (MetS) which occurs as a result of some complex obesity-induced metabolic changes. It is a common chronic liver disease characterized by excessive fat accumulation in the liver, the tendency to progress to more severe forms, and a corresponding increase in morbidity and mortality. Thus, effectively addressing the rising burden of the disease requires a thorough understanding of its complex interrelationship with obesity and MetS.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!