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A scientometric study on research trends and characteristics of oral leukoplakia and oral lichen planus.
J Dent Sci
January 2025
Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/purpose: Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP.
Materials And Methods: This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
The Dermatologic Oral Examination: Navigating the Oral Dermatoses Map.
J Am Acad Dermatol
January 2025
Mayo Clinic Arizona, Department of Dermatology, Scottsdale, AZ, USA.
Traditionally, dermatological education emphasizes hair, skin and nails in its curriculum. There is a practice gap with regard to knowledge of normal oral mucosa variants, performance of the oral examination, and competence in diagnosing and treating oral mucosal disorders. The oral mucosa falls within the purview of dermatology.
View Article and Find Full Text PDFNon-invasive screening for laryngeal cancer using the oral cavity as a proxy for differentiation of laryngeal cancer versus leukoplakia: A novel application of ESS technology and artificial intelligence supported statistical modeling.
Am J Otolaryngol
December 2024
Boston University Chobanian and Avedisian School of Medicine, 72 E. Concord Street, Boston, MA 02118, USA; Department of Otolaryngology, Boston Medical Center, 800 Harrison Avenue, Boston, MA 02118, USA. Electronic address:
Objective: This preliminary study tested whether non-invasive, remote Elastic Scattering Spectroscopy (ESS) measurements obtained in the oral cavity can be used as a proxy to accurately differentiate between patients with laryngeal cancer versus laryngeal leukoplakia.
Methods: 20 patients with laryngeal lesions [cancer (n = 10),leukoplakia (n = 10)] were clinically assessed and categorized by otolaryngologists per standard clinical practice. Patient demographics of age, race, sex, and smoking history were collected.
Comparison of Mast Cell Count in Oral Epithelial Dysplasia and Squamous Cell Carcinoma.
J Dent (Shiraz)
December 2024
Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Statement Of The Problem: Squamous cell carcinomas (SCCs) and premalignant disorders such as leukoplakia are common oral cavity lesions. Although these lesions are epithelial in nature, they are also associated with juxta-epithelial chronic inflammation. Mast cells play a significant role in inflammation initiation and propagation.
View Article and Find Full Text PDFConsidering SOD and miRNA analysis as potential prognostic markers in white lesion malignant transformation: A report of two cases.
Medicine (Baltimore)
December 2024
Department of Medical Biology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic.
Article Synopsis
- Predictive biomarkers can help identify oral leukoplakia with a higher risk of becoming cancerous, which is crucial for timely intervention.
- Two patients presented with oral burning sensations and white lesions, leading to a diagnosis confirmed through tissue analysis.
- The study found specific changes in microRNA expressions and antioxidant enzyme activities in patients, indicating a link between these molecular changes and the risk of malignant transformation.
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