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Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism.
Heliyon
January 2025
The First Affiliated Hospital of Chongqing Medical University, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, Chongqing, PR China.
Background: Several studies suggested the genetic association between IL10RA variants and susceptibility to Behcet's disease (BD). However, the precise mechanism of the association is still unknown. The purpose of this study was to investigate the mechanism underlying the genetic associations between IL10RA polymorphisms and the risk of BD.
View Article and Find Full Text PDFDefect Structures in Colloidal Crystals and Their Effect on Grating Diffraction Structural Color.
ACS Appl Mater Interfaces
January 2025
Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.
Colloidal crystals of micrometer-sized colloids create prismatic structural colors through the grating diffraction of visible light. Here, we develop design rules to engineer such structural color by specifically accounting for the effect of crystal defects. The local quality and grain size of the colloidal structure are varied by performing self-assembly in the presence of a direct current (DC) electric field.
View Article and Find Full Text PDFMicrostructure, wear, and corrosion properties of PEEK-based composite coating incorporating titania- and copper-doped mesoporous bioactive glass nanoparticles.
RSC Adv
January 2025
Department of Materials Science and Engineering, Institute of Space Technology Islamabad Pakistan
Poor wear- and corrosion-resistance of 316L SS implants are critical problems in orthopedic implants. This study aims to improve the wear- and corrosion-resistance of 316L SS through surface coating. In this study, a bilayer composite coating consisting of polyether ether ketone (PEEK) as the first layer, and titania (TiO)- and Cu-doped mesoporous bioactive glass nanoparticles (Cu-MBGNs) were deposited as the second layer on a 316L SS electrophoretic deposition (EPD).
View Article and Find Full Text PDFSynthesis of zwitterionic asymmetric and symmetric carboxy-imidazolium derivatives and their use in molecular interactions with bovine serum albumin.
Org Biomol Chem
January 2025
A. M. Butlerov Institute of Chemistry, Kazan Federal University, Kremlevskaya str. 18, Kazan 420018, Russia.
For the first time asymmetric and symmetric carboxytriazoleimidazolium derivatives with different structures were synthesized. The critical micellization concentration (CMC) value was estimated using a pyrene fluorescent probe and the solubility of Orange OT. The complexation ability of carboxytriazoleimidazolium derivatives toward bovine serum albumin (BSA) has been investigated by various physico-chemical methods: fluorescence spectroscopy, electrophoretic light scattering and circular dichroism.
View Article and Find Full Text PDFFunctional analysis of the type II toxin-antitoxin system ParDE in Streptococcus suis serotype 2.
BMC Vet Res
January 2025
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Streptococcus suis (S. suis) is a major pathogen in swine and poses a potential zoonotic threat, which may cause serious diseases. Many toxin-antitoxin (TA) systems have been discovered in S.
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