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Beyond Classification: A Unique Case of Self-Resolving Cutaneous Mucinosis Associated With Streptococcal Infection in a Child.
Pediatr Dermatol
December 2024
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months.
View Article and Find Full Text PDFSCLEREDEMA DIABETICORUM; A RARE DISEASE.
J Ayub Med Coll Abbottabad
November 2024
Pakistan Institute of Medical Sciences, Islamabad-Pakistan.
Scleredema Diabeticorum (SD) is a rare condition characterized by diffuse, symmetrical induration along with non-pitted swelling mostly on the upper back as a result of mucin being deposited in the dermis. It can also involve posterior neck, shoulders, and scalp. We report a case of 48 years old female patient from Pakistan, with uncontrolled diabetes mellites type 2 for the last 15 years, presenting with thickened skin at the back of the neck resulting in difficulty in neck and shoulder movements.
View Article and Find Full Text PDFVitamin D serum levels in patients with systemic sclerosis and very early systemic sclerosis (VEDOSS).
J Scleroderma Relat Disord
August 2024
Department of Advanced Medical and Surgical Sciences, "Luigi Vanvitelli" University of Campania, Naples, Italy.
Introduction: Vitamin D may be capable of interfering with the pathophysiological pathways involved in systemic sclerosis, by virtue of its well-known immunomodulatory effects. In this study, we aimed at evaluating the differences and the correlations between vitamin D levels in systemic sclerosis patients versus patients with very early systemic sclerosis.
Methods: One hundred twenty-six patients (80 definite systemic sclerosis and 46 very early systemic sclerosis) were included in this case control study.
Complete Dental Implant Restoration in an Individual With Systemic Sclerosis and Microstomia: A Case Report.
Case Rep Dent
October 2024
Department of Anatomy, Azad University of Medical Sciences, Tehran, Iran.
Systemic sclerosis (SS) is a debilitating disease that affects oral and any other tissues including skin, bone, blood vessels, and the connective tissues by excessive collagen accumulation. It is a difficult case for oral rehabilitation, let alone dental implantation. In this regard, only few studies have been conducted.
View Article and Find Full Text PDFTreatment-Refractory Scleredema Diabeticorum Managed With Re-irradiation Using Volumetric Modulated Arc Therapy.
Cureus
September 2024
Radiation Oncology, Vanderbilt University Medical Center, Nashville, USA.
Scleredema diabeticorum is a rare connective tissue complication of diabetes, most typically observed in adults with longstanding type 2 diabetes. Patients develop reticular dermis thickening with a peau d'orange appearance at the upper back and neck that occasionally extends over the deltoids and lower back. While considered a benign disorder, it may signify more significant diabetes and can be functionally and cosmetically impairing with insidious onset, few to no effective treatments, and low spontaneous remission potential.
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