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Structure Elucidation and Immunostimulatory Activity Evaluation of a Galactoglucan from Hance.
Foods
December 2024
State Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine, No.1899 Meiling Road, Nanchang 330103, China.
Hance has a medicinal history of thousands of years in treating cough, diabetes, and gastrointestinal system diseases, and it is also a medicine food homology (MFH) plant in China. To evaluate the pharmacological activities of polysaccharides from the rhizomes of , polysaccharides were initially obtained by hot-water extraction and the ethanol precipitation method. A homogenous polysaccharide designated as AOP-w was isolated by a DE-52 column.
View Article and Find Full Text PDFMulti-omics analysis reveals the pre-protective mechanism of Dendrobium flexicaule polysaccharide against alcohol-induced gastric mucosal injury.
Int J Biol Macromol
December 2024
College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China. Electronic address:
Dendrobium flexicaule (DF) is an endemic plant primarily found in the mountains of central China with important medicinal and edible values. In traditional Chinese medicine, DF has the effects of nourishing stomach and "Yin", and clearing heat. At present, no studies have explored the mechanisms by which Dendrobium flexicaule polysaccharides (DFP) exert pre-protect effects against alcohol-induced gastric mucosal injury.
View Article and Find Full Text PDFIn vitro fermentation characteristics and modulation effects of polysaccharide fractions from Schisandra sphenanthera on intestinal microflora.
Int J Biol Macromol
December 2024
Beijing Key Laboratory of Forest Food Processing and Safety, College of Biological Science & Biotechnology, Beijing Forestry University, Beijing 100083, China. Electronic address:
Article Synopsis
- SSPs (Schisandra Sphenanthera polysaccharides) were obtained using gradient ethanol precipitation, resulting in three fractions: SSP40, SSP60, and SSP80, each with distinct physicochemical properties.
- SSP80 had a lower molecular weight and a unique monosaccharide composition, leading to increased porosity compared to the other fractions.
- After fermentation, SSP80 significantly boosted short-chain fatty acid production and improved the balance of intestinal microflora by enhancing beneficial bacteria and reducing potentially harmful ones.
Immunostimulatory effects of rhamnogalacturonan-I fraction purified from Glycyrrhiza glabra roots on cyclophosphamide-induced immunosuppressed mice.
Int J Biol Macromol
December 2024
Department of Food Science and Biotechnology, Kyonggi University, Suwon 16227, Republic of Korea. Electronic address:
The present study aimed to investigate the immunostimulatory activities of polysaccharides purified from Glycyrrhiza glabra root. First, five polysaccharide fractions were separated from G. glabra through hot water extraction, ethanol precipitation, enzymatic hydrolysis, and size exclusion chromatography.
View Article and Find Full Text PDFStructural Characteristics and Immunological Function of a New Non-Starch Polysaccharide from Taro.
Foods
November 2024
Jiangxi Province Key Laboratory of Vegetable Cultivation and Utilization, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.
Taro is a tuber crop that is used for nutritional and medicinal purposes due to its abundance of non-starch polysaccharides (NSPs). taro is a local variety in Southern China, but the characteristics and bioactivities of its NSPs are currently unknown. In this study, NSPs were isolated from the corms of taro using hot-water extraction, ion-exchange chromatography, and ethanol precipitation; their molecular weight, monosaccharide composition, structural formulae, and immunomodulatory effects were examined.
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