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Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening.
Sci Rep
January 2025
Molecular Biology and Stem Cell Research Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science & Technology, Chennai, Tamilnadu, India.
Model organisms are vital for biomedical research and drug testing but face high costs, complexity, and ethical issues. While newer techniques like organoids and assembloids have shown improvements, they still remain inadequate in addressing all research needs. In this study, we present a new method for maintaining the prostate gland of the earthworm, Eudrilus eugeniae ex vivo and examine its potential for regeneration and drug screening.
View Article and Find Full Text PDFKinetic and isothermal study of dye absorption using pre-treated natural fabrics using polyamine compounds.
Sci Rep
January 2025
Finishing of Cellulose-based Fibres Department, National Research Centre, Pretreatment and Textile Research and Technology Institute, 33 El-Behouth St. (former El-Tahrir str.), Dokki, P.O. 12622, Giza, Egypt.
The study examined the use of cationic polymers (Polyethyleneimine and chitosan) in treating fabrics like cotton, wool, and cotton/wool (70/30) to improve their dyeability and printability. The study examined factors such as dye concentration, time, and temperature for the dyeing process. Results showed that all dyed and printed fabrics treated with polyethyleneimine and chitosan increased color strength by significant percentages.
View Article and Find Full Text PDFBoosting Electrode Performance and Bubble Management via Direct Laser Interference Patterning.
ACS Appl Mater Interfaces
January 2025
Institute of Fluid Dynamics, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany.
Article Synopsis
- Laser-structuring techniques, particularly Direct Laser Interference Patterning, can significantly enhance the performance of pure Ni electrodes in water electrolysis by optimizing their structure.
- A study revealed that the spatial distance between laser-structures is critical for improving electrode performance, resulting in an increase in the electrochemically active surface area by up to 12 times compared to nonstructured electrodes.
- Optimal structuring leads to lower onset potential and overpotential during the oxygen evolution reaction due to the superhydrophilic surface, which enhances bubble growth dynamics and minimizes electrode resistance.
Comprehensive evaluation of low-carbon cementitious materials prepared with industrial by-product calcium carbide residue (CCR) as alkali source.
Environ Res
January 2025
Science and Technology Innovation Center of Smart Water and Resource Environment, Northeastern University, Shenyang 110819, China; School of Resources and Civil Engineering, Northeastern University, Shenyang 110819, China; Liaoning Institute of Technological Innovation in Solid Waste Utilization, Northeastern University, Shenyang 110819, China.
The preparation of low-carbon cementitious materials through the synergistic coupling of multiple solid wastes has great potential for development, which can improve the problems of resource shortage and environmental pollution. In this paper, a new type of supersulfated cement was developed by using calcium carbide residue (CCR) as an alkaline activator. The effects of CCR content on the mechanical properties and hydration behaviors of the samples under steam curing conditions were discussed.
View Article and Find Full Text PDFImpact of Ligand-Induced Oligomer Dissociation on Enzyme Diffusion, Directly Observed at the Single-Molecule Level.
Nano Lett
January 2025
Chemical Biology 1, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.
The existence of the phenomenon of enhanced enzyme diffusion (EED) has been a topic of debate in recent literature. One proposed mechanism to explain the origin of EED is oligomeric enzyme dissociation. We used mass photometry (MP), a label-free single-molecule technique, to investigate the dependence of the oligomeric states of several enzymes on their ligands.
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