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J Bone Miner Res
March 2025
Division of Bone and Mineral Diseases, Washington University in St. Louis, MO, United States.
Background: A significant number of kidney transplant recipients have low BMD. We hypothesized that calcitriol administration over the first year post-transplantation would protect the cortical skeleton in recipients managed without corticosteroids by suppressing PTH and bone remodeling.
Methods: In this double-blind, placebo-controlled trial, 67 participants aged ≥18 years on corticosteroid-sparing immunosuppressive regimen were randomized to daily calcitriol 0.
On September 27, 2024, a discussion-based working meeting on the issue of vitamin D deficiency in patients with overweight and obesity was held in Vladikavkaz.The meeting aimed to evaluate the relationship between vitamin D deficiency, overweight, and associated comorbidities, as well as to explore modern strategies and practical approaches for managing such patients in endocrinology practice. The resolution of the meeting was developed by its participants, comprising leading endocrinologists.
View Article and Find Full Text PDFTopical diagnosis can be severely complicated in patients with primary hyperparathyroidism (PHPT) due to the ectopic placement of parathyroid gland (PTG) formations. We report a clinical case of PHPT in an 84-year-old patient caused by ectopic PTG adenoma located behind the right internal jugular vein at the level of the right submandibular gland. The impossibility of surgery for a long time due to the absence of a topical diagnosis has necessitated conservative treatment was required to get the hypercalcemia under control.
View Article and Find Full Text PDFNat Commun
March 2025
Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
We have previously shown that high-dose vitamin D improved weight gain and neurodevelopmental indices in children receiving standard therapy for uncomplicated severe acute malnutrition (SAM). Here we present results of a randomised placebo-controlled trial in Lahore, Pakistan, to determine whether two oral doses of 200,000 international units (IU) vitamin D (the first administered on or before the day of hospital discharge and the second administered 14 days later) would benefit children aged 6-59 months during the convalescent phase of complicated SAM. Eligible participants were individually randomised to intervention vs.
View Article and Find Full Text PDFNutr Metab Cardiovasc Dis
February 2025
Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, SA, 5042, Australia. Electronic address:
Background And Aims: Peripheral arterial disease (PAD) is a cardiovascular disease affecting approximately 6 % of the population. The condition is associated with claudication, non-healing ischemic ulceration, and a systemic pro-inflammatory and pro-oxidative state. Recently, nutrition therapy is exploring immunonutrition as a novel dietary strategy to reduce the progression of atherosclerosis.
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