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Although hemoplasma infection has been widely described in animals, a few studies have been conducted involving human populations, mostly as case reports. This was a cross-sectional epidemiological study that accessed hemoplasma infection in individuals and dogs from ten Indigenous communities of southern and southeastern Brazil. A total of 23/644 (3.

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The DHH-DHHA1 domain phosphodiesterase of Mycoplasma bovis employs multiple strategies to modulate macrophage cellular processes.

Int J Biol Macromol

February 2025

The State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. Electronic address:

The multifunctional DHH-DHHA1 phosphodiesterase plays critical roles in bacterial physiological regulation and host-pathogen interactions. In Mycoplasma bovis, the DhhP-type phosphodiesterase MbovP328 exhibits both phosphodiesterase and nanoRNase activities, with the H291 residue critical for phosphodiesterase function. Transposon insertion in Mbov_0328 inactivated both activities in the mutant T9.

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Mycoplasma pneumonia is a chronic respiratory disease that seriously affects the health of sheep. To date, little information is available about the damage caused by Mycoplasma ovipneumoniae (MO) pneumonia to host lungs. Here, after sheep were infected with MO for 28 days, severe inflammatory reactions and pathological damage occurred.

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