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AIHEMAF-P: An Innovative Healthcare Model for Atrial Fibrillation Patients.
Pharmacy (Basel)
December 2024
R&D for Clinical Activity in Telemedicine, Italian National Health Agency-AGENAS, 00187 Rome, Italy.
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias of clinical relevance and a major cause of cardiovascular morbidity and mortality. Following a diagnosis of AF, patients are directed towards therapy with anticoagulant drugs to reduce the thromboembolic risk and antiarrhythmics to control their cardiac rhythm, with periodic follow-up checks. Despite the great ease of handling these drugs, we soon realized the need for follow-up models that would allow the appropriateness and safety of these pharmacological treatments to be monitored over time.
View Article and Find Full Text PDFUncommon Presentation of Hypersplenism in Adult Sickle Cell Disease Patients: A Rare Case Report.
Am J Case Rep
September 2024
Department of Surgery, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Article Synopsis
- Hypersplenism is a condition where blood cells are destroyed rapidly, characterized by splenomegaly, cytopenias, and increased bone marrow activity, and can be secondary to diseases like sickle cell disease, specifically hemoglobin sickle C disease (HbSC).
- A 41-year-old woman with HbSC presented with complications from splenomegaly and anemia due to hypersplenism, leading to her undergoing a splenectomy after preoperative splenic artery embolization.
- Hypersplenism can lead to severe complications like splenic sequestration crises, affecting adults rarely but is associated with significant spleen enlargement, as demonstrated by the patient’s spleen measuring 21.1 cm, necessitating effective
Relapse Risk Factors for Immune-Mediated Hemolytic Anemia: A Retrospective Study of 163 Dogs.
J Am Anim Hosp Assoc
September 2024
BluePearl North East Portland, Portland, Florida (E.W.).
Immune-mediated hemolytic anemia (IMHA) is defined as an immune-mediated destruction of erythrocytes. Relapses are recognized, but risk factors are poorly defined. We hypothesized that a lower packed cell volume (PCV) on presentation, more transfusions during hospitalization, or a higher total bilirubin would be associated with an increased risk of relapse.
View Article and Find Full Text PDFBiologic use is not associated with postoperative complications in patients with Crohn's disease undergoing stoma reversion.
ANZ J Surg
December 2023
Department of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Purpose: Stoma creation is a common procedure in patients with Crohn's disease (CD), and early prophylaxis with biologics is recommended for high-risk patients. However, the effect of biologic exposure on morbidity after stoma closure remains unknown. Therefore, this study aimed to investigate the impact of biologic use on the occurrence of complications in CD patients following stoma closure.
View Article and Find Full Text PDFA Review of Hematological Complications and Treatment in COVID-19.
Hematol Rep
October 2023
Department of Translational Research, Western University of Health Sciences, Pomona, CA 91766, USA.
Article Synopsis
- * Patients with severe COVID-19 often experience complications like thrombocytopenia and leukopenia, which can worsen health outcomes and necessitate cautious treatment decisions, especially for those who are immunocompromised.
- * The review explores the relationship between COVID-19 and hematological changes, emphasizing that these changes can serve as important indicators for treatment responses and may inform adjustments in therapy for affected patients.
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