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Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy.
Theranostics
January 2025
Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Activatable multifunctional nanoparticles present considerable advantages in cancer treatment by integrating both diagnostic and therapeutic functionalities into a single platform. These nanoparticles can be precisely engineered to selectively target cancer cells, thereby reducing the risk of damage to healthy tissues. Once localized at the target site, they can be activated by external stimuli such as light, pH changes, or specific enzymes, enabling precise control over the release of therapeutic agents or the initiation of therapeutic effects.
View Article and Find Full Text PDFGovernment and community strategies in Pernambuco, Brazil, to face COVID-19.
Cien Saude Colet
December 2024
Laboratório de Avaliação de Situações Endêmicas Regionais, Departamento de Endemias Samuel Pessoa, Escola Nacional de Saúde Pública Sérgio Arouca, Fundação Oswaldo Cruz (Fiocruz). R. Leopoldo Bulhões 1480, Manguinhos. 21041-210 Rio de Janeiro RJ Brasil.
This case study analyzed arrangements and strategies of the network actors in the Special Indigenous Sanitary District (DSEI) Pernambuco's territory to guarantee the right to health of Indigenous populations during the COVID-19 pandemic. This work was carried out through document analysis, workshops, and field research. The Contingency Plan for COVID-19 in Indigenous Peoples of DSEI Pernambuco included surveillance actions, laboratory and pharmaceutical assistance, communication, and management.
View Article and Find Full Text PDFImplementation of the Indigenous Health Policy: an ethnographic analysis of healthcare practices in the Upper Solimões River.
Cien Saude Colet
December 2024
Laboratório de Situação de Saúde e Gestão do Cuidado de Populações Indígenas e outros grupos vulneráveis (SAGESPI), Instituto Leônidas e Maria Deane, Fiocruz-AM. R. Teresina 476, Adrianópolis. 69057-070 Manaus AM Brasil.
This study analyzes the implementation of the Indigenous Health Policy, focusing on the care practices of health teams of the Indigenous Health Care Subsystem in the Upper Solimões River in the Amazon region. Using ethnography as a methodological resource, the dynamics among participants, discourses, and power in the implementation of the policy are investigated, revealing a complex interconnection between practices and other contextual realities. Three phenomena emerge as critical influences on care practices: the medical-care model, the sanitation model, and the culture of performance.
View Article and Find Full Text PDFChanges and continuities in gambling careers during the COVID-19 pandemic: a longitudinal qualitative study of regular sports bettors in Britain.
BMC Public Health
January 2025
Institute for Social Marketing and Health, University of Stirling, Stirling, Scotland.
Background: To explore continuities and changes in gambling behaviour during the COVID-19 pandemic and the factors that influenced these among a sample of regular sports bettors.
Methods: A longitudinal qualitative study using in-depth interviews. Sixteen sports bettors living in Britain took part in the first interviews in July-November 2020, and 13 in the follow-up interviews in March-September 2021.
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