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Toxicity of standing milkvetch infected with in white mice.
Front Vet Sci
January 2025
State Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, College of Pastoral Agriculture Science and Technology, Engineering Research Center of Grassland Industry, Ministry of Education, Lanzhou University, Lanzhou, China.
Introduction: Standing milkvetch () is widely distributed in the wild in Eurasia and North America and has been bred for cultivated forage in China. Yellow stunt and root rot disease caused by is the primary disease of standing milkvetch. promotes the production of swainsonine in the plant.
View Article and Find Full Text PDFComparative analysis of anticoagulant influence on PMI estimation based on porcine blood metabolomics profile measured using GC-MS.
Front Mol Biosci
January 2025
Department of Forensic Medicine, Medical University of Bialystok, Bialystok, Poland.
Introduction: Accurate post-mortem interval (PMI) estimation is essential in forensic investigations. Although various methods for PMI determination have been developed, only an approximate estimation is still achievable, and an accurate PMI indication is still challenging. Therefore, in this study, we employed gas chromatography-mass spectrometry (GC-MS)-based metabolomics to assess post-mortem changes in porcine blood samples collected with and without the addition of anticoagulant (EDTA).
View Article and Find Full Text PDFNAFPD exacerbation by hyperlipidemia combined with hyperuricemia: a pilot rat experiment in lipidomics.
Front Nutr
January 2025
Department of Ultrasound, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Background: Hyperuricemia and non-alcoholic fatty pancreas disease (NAFPD) are prevalent metabolic diseases, but the relationship between them remains underexplored.
Methods: Eighteen Sprague-Dawley rats were randomly assigned to three groups: normal (CON), high-fat (PO), and high-fat high-uric acid (PH). After 12 weeks, serum uric acid (SUA) and triacylglycerol levels were measured.
Filarial parasite infection prevalence in field-caught mosquitoes from Connecticut, United States.
J Med Entomol
January 2025
Center for Vector Biology & Zoonotic Diseases, Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, CT, USA.
Filarial nematodes are parasitic roundworms transmitted by mosquitoes that can cause morbidity and mortality for their human and animal hosts. The filariae community, specifically infection prevalence of heartworm, Dirofilaria immitis (Filarioidea: Onchocercidae) (Leidy), and its primary mosquito vector species, has not been described in Connecticut since 1977. In light of the recent invasion and establishment of an important filariasis vector, Aedes albopictus (Diptera: Culicidae) (Skuse), we used molecular-based sequencing methods to identify filarial species infecting field-caught mosquitoes in Connecticut, United States.
View Article and Find Full Text PDFObesity increases DNA damage in the breast epithelium.
Breast Cancer Res
January 2025
Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Obesity is a modifiable risk factor for breast cancer. Yet, how obesity contributes to cancer initiation is not fully understood. The goal of this study was to determine if the body mass index (BMI) and metabolic hallmarks of obesity are related to DNA damage in normal breast tissue.
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