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Ternary Metal (W-Ni-Sr) Oxide@Polypyrrole Nanotubes: A New Frontier in the Electrochemical Detection of Promethazine Hydrochloride (PMHC).
Langmuir
January 2025
Department of Chemistry, School of Applied Sciences, REVA University, Bengaluru 560064, Karnataka, India.
Promethazine hydrochloride (PMHC) is a vital drug that is used as an anticholinergic, antipsychotic, antihistaminic, analgesic, sedative, and neuroleptic. However, the overdosage of PMHC also causes reproductive variations, cardiac changes, hypotension, and endocrinal variations. Hence, the detection of PMHC is crucial.
View Article and Find Full Text PDFPromethazine is not a good option to aid sleep quality, especially for people using psychiatric services.
BJPsych Bull
January 2025
Division of Psychiatry, Imperial College London, UK.
Article Synopsis
- Promethazine, often prescribed as a sleep aid, lacks strong evidence for effectiveness and can interfere with better long-term treatments.
- It poses risks due to its potential for addiction and undesirable side effects, especially in mental health patients.
- Cognitive-behavioral therapy for insomnia is suggested as a preferred alternative based on guidelines from NICE.
Pharmacological Strategies for Postdischarge Nausea and Vomiting: Evidence-based Review Update.
J Perianesth Nurs
December 2024
Graduate Programs of Nurse Anesthesia, Texas Wesleyan University, Fort Worth, TX.
Purpose: Evaluate the effectiveness of various drugs in preventing postdischarge nausea and vomiting (PDNV).
Design: Systematic review.
Methods: A search for evidence was conducted in PubMed, CINAHL, Cochrane Collaboration, and Google Scholar and gray literature.
Management of Antenatal Agitation in a Tertiary Care Center in Central India: A Secondary Analysis.
Cureus
November 2024
Psychiatry, Mahatma Gandhi Memorial Medical College, Indore, IND.
Background The presence of psychiatric symptoms in pregnancy is a common occurrence that requires swift and effective management to avoid harm to self, caregivers, staff, and, above all, the reliant fetus. However, there is a dearth of knowledge, practical guidelines, and research in the context of managing agitated states of antenatal patients. To bridge this critical knowledge gap, this research endeavors to illuminate the practices surrounding the management of agitated pregnant women with respect to psychiatric emergencies in a tertiary care hospital.
View Article and Find Full Text PDFThis study aims to investigate the effect of promethazine (PMZ) on hippocampal neuronal injury through network pharmacology and in vivo experiments. Network pharmacology: The intersection genes of PMZ and Alzheimer Disease (AD) were obtained, and the core genes of PMZ in AD were screened. The intersection genes were enriched by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses.
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