Irradiation at 254 millimicrons transforms 5-ethyldeoxyuridine to deoxyuridine by way of photohydration of the 5,6 bond and elimination of ethanol. At wavelengths to the red side of 265 millimicrons, photodimerization is the principal reaction, with a pronounced oxygen effect. The results are related to the photochemistry of thymidine and of bacteriophages containing incorporated 5-ethyluracil in place of thymine.

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.161.3847.1248DOI Listing

Publication Analysis

Top Keywords

5-ethyldeoxyuridine thymidine
4
thymidine analog
4
analog photochemical
4
photochemical transformation
4
transformation irradiation
4
irradiation 254
4
254 millimicrons
4
millimicrons transforms
4
transforms 5-ethyldeoxyuridine
4
5-ethyldeoxyuridine deoxyuridine
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!