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http://dx.doi.org/10.1016/s0015-0282(16)36731-0 | DOI Listing |
Fertil Steril
July 2018
Division of Urology, Brigham and Women's Hospital, Boston, Massachusetts.
The method employed is simple, harmless and-above all-not objectionable to patients. In cases such as those described, it is preferable to other therapeutic measures, which are too often both prolonged and useless. -Schellen T.
View Article and Find Full Text PDFHum Reprod
July 2017
Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, DK-2400 Copenhagen NV, Denmark.
Study Question: Is male factor infertility associated with an increased risk of developing diabetes?
Summary Answer: The study provides evidence that male factor infertility may predict later occurrence of diabetes mellitus with the risk being related to the severity of the underlying fertility problem.
What Is Known Already: Previous cross-sectional studies have shown an increased prevalence of comorbidities among infertile men when compared to controls.
Study Design, Size, Duration: In this prospective cohort study, 39 516 men who had since 1994 undergone fertility treatment with their female partner were identified from the Danish national IVF register, which includes data on assumed cause of couple infertility (male/female factor, mixed and unexplained infertility) and type of fertility treatment.
Hum Reprod
January 2017
Human Molecular Genetics Research Group, Institute of Molecular and Cell Biology; Institute of Biomedicine and Translational Medicine, University of Tartu, 51010 Tartu, Estonia.
Study Question: What are the primary causes of severe male factor infertility?
Summary Answer: Although 40% of all patients showed primary causes of infertility, which could be subdivided into three groups based on the severity of their effect, ~75% of oligozoospermia cases remained idiopathic.
What Is Known Already: There are few large-scale epidemiological studies analyzing the causes of male factor infertility.
Study Design, Size, Duration: A prospective clinical-epidemiological study was conducted at the Andrology Centre, Tartu University Hospital between 2005 and 2013, recruiting male partners of couples failing to conceive a child for over ≥12 months.
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