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The utility of the normal thin section skin biopsy in the assessment of systemic/extracutaneous disease and small fiber neuropathy.
Clin Dermatol
December 2024
New York- Presbyterian/Weill Cornell Medicine Department of Pathology and Laboratory Medicine, New York, NY, USA.
Article Synopsis
- Various systemic diseases can show abnormalities on a normal skin biopsy, which can assist in making accurate diagnoses, especially for conditions like thrombotic microvascular diseases and dysautonomia syndromes.
- A review of skin biopsy data revealed specific patterns and markers that are linked to certain diseases, including increased C5b-9 deposition and signaling changes related to interferon.
- The findings emphasize that skin biopsies provide valuable insights into multi-organ diseases, highlighting their importance in clinical evaluations.
Clinical efficacy of endovascular revascularization combined with vacuum-assisted closure for the treatment of diabetic foot.
World J Diabetes
July 2024
Department of Vascular Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
Background: The diabetic foot is a common cause of disability and death, and comorbid foot infections usually lead to prolonged hospitalization, high healthcare costs, and a significant increase in amputation rates. And most diabetic foot trauma is complicated by lower extremity arteriopathy, which becomes an independent risk factor for major amputation in diabetic foot patients.
Aim: To establish the efficacy and safety of endovascular revascularization (ER) combined with vacuum-assisted closure (VAC) for the treatment of diabetic foot.
Critical Limb Ischemia Due to Suspected Buerger's Disease in an Adolescent Patient: A Case Report.
Cureus
April 2024
Department of Public Health, University Hospital Federico II, Naples, ITA.
Buerger's disease is a segmental and inflammatory syndrome affecting relatively young individuals primarily and occurs with occlusion of small to medium-sized vessels in their extremities. The typical age for symptoms to appear is between 35 and 50 years in smoking patients. The disease is not manifested in children or the elderly.
View Article and Find Full Text PDFEarly hemodynamics after tibial transverse transport in patients with nonarterial stenosis and arterial stenosis diabetic foot.
World J Diabetes
December 2023
Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Article Synopsis
- The study looked at two types of diabetic foot problems: one caused by narrowed arteries (arterial stenosis) and one not (non-arterial stenosis).
- It aimed to see how a specific treatment called tibial transverse transport (TTT) helped improve blood flow and heal wounds in patients with diabetic foot ulcers.
- Results showed that patients with non-arterial stenosis healed their wounds faster compared to those with arterial stenosis.
Literature review of transcutaneous electrical nerve stimulation in peripheral arterial occlusive disease of the lower limbs.
J Med Vasc
September 2023
Service de médecine vasculaire, Grenoble University Hospital, BP 217, 38043 Grenoble Cedex 09, France.
Unlabelled: The therapeutic challenge in peripheral arterial occlusive disease (PAD) is often to increase walking distance, improve pain or heal a wound when PAD is symptomatic. Walking rehabilitation or surgical revascularization techniques are limited. Others strategies as alternatives and/or complementary treatments are needed.
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