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Autistic adults experience greater rates of anxiety and depression compared to the general population. Compassion-focused therapy interventions, aimed at promoting self-compassion capabilities, have shown efficacy in improving mental health outcomes in autistic and non-autistic samples suffering from self-criticism that contribute to difficulties in emotion regulation. We explored the experiences of autistic adults during a brief one-week online self-compassion exercise to evaluate it's feasibility and acceptability through self-report, experience sampling, and parasympathetic activity measured via HRV.

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Background: In the USA, many states, including Colorado, have increased criminal penalties for illicit opioid possession, which may alter overdose risk. We aimed to evaluate the relationship between Colorado's increased drug-related criminal legal penalties, risk of overdose, and substance use patterns.

Methods: We used concept mapping - a mixed-methods approach used to develop a conceptual understanding of an issue from a community lens - to engage with people with living and/or lived experience with the criminal legal system, substance use, and/or overdose, their loved ones, and service providers.

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Efficient separation and preconcentration of nanoparticles are crucial in a wide range of biomedical applications, particularly as target substances continue to diminish in size. In this study, we introduce an electric field-assisted membrane system that synergistically combines oversized-pore membranes with an electrokinetic particle retention mechanism. Utilizing Ti/Au-coated poly(tetrafluoroethylene) (PTFE) membranes, our approach generates electrokinetic forces to effectively separate and retain charged nanoparticles even smaller than the pores, achieving a separation efficiency over 99% and a preconcentration factor of 1.

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Intricate crosstalk among various lung cell types is crucial for orchestrating diverse physiological processes. Traditional two-dimensional and recent three-dimensional (3D) assay platforms fail to precisely replicate these complex communications. Many lung models do not effectively reflect the multicellular complexity of lung tissue.

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In Southern U.S. states with high HIV incidence and low HIV Pre-Exposure Prophylaxis (PrEP) uptake, enhanced efforts to increase interest in and willingness to use PrEP are needed.

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