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Health and Liver Diagnostic Markers Influencing Glycemia in Subjects with Prediabetes: Preview Study.
Diagnostics (Basel)
December 2024
Centre for Nutrition Research, Department of Nutrition, Food Science, Physiology and Toxicology, University of Navarra, 31009 Pamplona, Spain.
Introduction: Glucose homeostasis may be dependent on liver conditions and influence health-related markers and quality of life (QoL) objective measurements. This study aimed to analyze the interactions of glycemia with liver and health status in a prediabetic population.
Subjects And Methods: This study included 2220 overweight/obese prediabetics from the multinational PREVIEW project.
T cell dynamics with neoadjuvant immunotherapy in head and neck cancer.
Nat Rev Clin Oncol
December 2024
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Immune-checkpoint inhibitors (ICIs) are being tested as neoadjuvant therapies in various solid tumours, including in patients with head and neck squamous cell carcinoma (HNSCC), with promising results. Key findings thus far include that this approach is well-tolerated with favourable clinical outcomes including promising pathological response rates in initial studies. Pathological responses are likely to be increased by combining other agents with anti-PD-(L)1 antibodies.
View Article and Find Full Text PDFAnalysis of the interrelationship between precipitation and confirmed dengue cases in the city of Recife (Brazil) covering climate and public health information.
Front Public Health
November 2024
Department of Atmospheric Sciences, Institute of Astronomy, Geophysics and Atmospheric Sciences (IAG), University of São Paulo, São Paulo, Brazil.
Article Synopsis
- Large-scale epidemics of arboviruses like dengue emphasize the importance of understanding the environmental factors that affect vector populations, particularly in urban areas.
- A study conducted in Recife, Brazil, found a correlation between rainfall and confirmed dengue cases, with higher incidences during the rainy season, though surprising outbreaks occurred during drier months.
- The research highlights the complexity of dengue dynamics, indicating that while precipitation is important, other factors such as serotype circulation and broader climate influences also play crucial roles in disease spread.
Triiodothyronine (T), but not resting metabolic rate correlates positively with per- and polyfluoroalkyl substances (PFAS) in Arctic terns.
Environ Res
December 2024
Department of Biology, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway; Department of Arctic Technology, University Centre in Svalbard, P.O. Box 156 N-9171 Longyearbyen, Norway. Electronic address:
In Arctic seabirds, positive correlations between per- and polyfluoroalkyl substances (PFAS) and thyroid hormones (THs) and resting metabolic rate (RMR) have been documented. Herein we investigated levels and patterns of PFAS in Arctic terns (Sterna paradisaea) nesting in Kongsfjorden, Svalbard (Norway), and if circulating concentrations of PFAS correlated with their circulating concentrations of TH, and the RMR of the birds. The hypothesis was that there will be positive correlations between PFAS, TH, and RMR, indicating that PFAS-induced increases in plasma THs could be responsible for the increased RMR.
View Article and Find Full Text PDFAssessing the impact of human activities on ecosystem asset dynamics in the Yellow River Basin from 2001 to 2020.
Sci Rep
September 2024
School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou, 341000, China.
The intensification of human activities in the Yellow River Basin has significantly altered its ecosystems, challenging the sustainability of the region's ecosystem assets. This study constructs an ecosystem asset index for the period from 2001 to 2020, integrating it with human footprint maps to analyze the temporal and spatial dynamics of ecosystem assets and human activities within the basin, as well as their interrelationships. Our findings reveal significant improvement of ecosystem assets, mainly attributed to the conversion of farmland back into natural habitats, resulting in a 15,994 km increase in ecological land use.
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