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Oral SARS-CoV-2 Infection and Risk for Long Covid.
Rev Med Virol
March 2025
Department of Periodontics, University of Illinois Chicago, Chicago, Illinois, USA.
SARS-CoV-2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post-acute sequelae COVID-19 (PASC) and other oral and non-oral pathologies. While pre-existing inflammatory oral diseases provides a conducive environment for the virus, acute infection and persistence of SARS-CoV-2 can also results in oral microbiome dysbiosis that further worsens poor oral mucosal health. Indeed, oral PASC includes periodontal diseases, dysgeusia, xerostomia, pharyngitis, oral keratoses, and pulpitis suggesting significant bacterial contributions to SARS-CoV-2 and oral tissue tropism.
View Article and Find Full Text PDFFlexible microcolumn array-based silk fibroin for sweat glucose monitoring.
Anal Chim Acta
May 2025
College of Textile Science and Engineering, Jiangnan University, 1800Lihu Road, Wuxi, 214122, China. Electronic address:
Flexible sweat sensors possess the special potential for continuous non-invasive monitoring of human blood glucose. We put forward a flexible microcolumn array sensor, which is designed for health monitoring by means of detecting glucose levels in sweat and capturing physiological signals related to human movement. With the combination of silk fibroin (SF), waterborne polyurethane (PU), and multi-walled carbon nanotubes (MWCNT), this microcolumn film electrode is able to effectively function as a strain sensor benefiting from the superior mechanical performance of PU.
View Article and Find Full Text PDFEffect of the overexpression of the GGP1 gene on cell wall remodelling and redox state in the tomato fruit.
Plant Sci
March 2025
Institute of Agrophysics, Polish Academy of Sciences, Doświadczalna 4, 20-290 Lublin, Poland. Electronic address:
Tomato fruit ripening is a complex physiological process that involves morphological, anatomical, biochemical, and molecular alterations. One of these changes occurring during ripening is the softening of the fruit, which is attributed to modifications in the biosynthesis and degradation of individual cell wall components, i.e.
View Article and Find Full Text PDFCloning, Expression, Characterization and in silico studies of L-asparaginase from Vibrio sp. (GBPx3).
Biochimie
March 2025
Department of Medical Biotechnology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran; Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran. Electronic address:
L-asparaginase is a critical therapeutic enzyme for treating acute lymphoblastic leukemia (ALL), a common childhood malignancy. In this study, the L-asparaginase coding sequence from halophilic Vibrio sp. (GBPx3) was cloned, expressed in Escherichia coli, and characterized.
View Article and Find Full Text PDFmiR-7977 regulates the locomotor behavior by targeting diuretic hormone and SIFamide receptors in Tribolium castaneum.
Int J Biol Macromol
March 2025
Guizhou Provincial Key Laboratory for Agricultural Pest Management of the Mountainous Region, Institute of Entomology, Guizhou University, Guiyang, Guizhou, China; Institute of Plant Health and Medicine, Guizhou University, Guiyang, China. Electronic address:
Insect neuropeptides are crucial for chemical communication, influencing growth, metabolism, and behavior. MicroRNAs (miRNAs), as non-coding RNAs, primarily regulate target gene expression. However, the co-regulation between miRNAs and neuropeptides in modulating locomotor behavior remains poorly understood.
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