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The peculiarities of cytokines as compounds of immunogenesis are shown in the patients having acute (A) and chronic (Ch) pyelonephritis (PN). The combination of antibacterial therapy with Nukleinat and Galavit promotes the positive changes of cytokin-producing ability of immunocompetent cells and decrease in the level of proinflammation cytokines in blood and urine, secretory leucocyte protease inhibitor (SLPI) in urine. In children with PN and adult patients with diagnostically elevated titres of antibodies (IgG) to Herpes simplex virus, Cytomegalovirus are shown the positive effects of Kanephron® H and Proteflazidum, accordingly.
View Article and Find Full Text PDFVestn Ross Akad Med Nauk
July 2002
The clinical and immunological characteristics of lymphoid tumors were compared in 591 children with acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL). Comprehensive investigation of a tumor cell by using cytological, morphological, and immunological studies revealed the most significant criteria for differential diagnosis of ALL and NHL in children and showed the specific features of the site of a tumor and the extent of its growth in ALL and NHL in relation to the immunological affiliation of a tumor cell. The predominance of immature forms, such as stem-cell CD34+, pre-pre-B, pre-B and less commonly T-cell forms with almost none peripheral B- and T-cell markers could be immunophenotypically detected in ALL.
View Article and Find Full Text PDFRadiats Biol Radioecol
June 2000
Institute of Immunology, Ministry of Health of Russia, Moscow.
Clinical investigation of immune and allergic state of 633 adult dwellers of the Middle Ural region was carried out. The first (occupational) group consisted of 479 workers of the industrial plant, most of which exposed to negative factors such as radiation, harmful chemical substances and stress. The second (control) group consisted of 154 town-dwellers, who did not work at the industrial plant.
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