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Heterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD.
Int J Chron Obstruct Pulmon Dis
July 2019
Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada,
Background: The burden of symptoms varies markedly between patients with COPD and is only weakly correlated with lung function impairment. While heterogeneity in lung function decline and exacerbations have been previously studied, the extent of heterogeneity in symptoms and the factors associated with this heterogeneity are not well understood.
Methods: A sample of the general Canadian population ≥40 years with persistent airflow limitation was followed for up to 3 years.
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