The results of study of the rhythms of secretion of 11-OCS, synthesis and metabolism of glucose, formation of urea and esters of fatty acids in male rats in the course of 12 hours of the daily period are presented in this work. A definite rhythmic character and conjugation of the processes of corticosteroid secretion and carbohydrate, fat and protein metabolism were revealed. Participation of the adrenal cortex hormones (glucocorticoids) in the regulation of direction of the carbohydrate metabolism by the type of glycolysis, hexosomonophosphate way and gluconeogenesis is discussed.

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