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Maternal and fetal outcomes in those with autoimmune connective tissue disease.
Clin Rheumatol
January 2025
Division of Cardiology, University of Minnesota, Minneapolis, USA.
Article Synopsis
- Autoimmune connective tissue diseases (CTDs) such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA) significantly impact pregnant women, leading to maternal and fetal complications.
- A retrospective study analyzed data from over 18 million deliveries and found higher odds of maternal death, acute kidney injury, and severe complications in mothers with CTDs, alongside increased risks of adverse fetal outcomes like stillbirth and preterm labor.
- The findings highlight the need for specific preconception counseling and management approaches to improve health outcomes for pregnant women with autoimmune CTDs.
Reproductive Health in Scleroderma, Vasculitis, and Sjögren Syndrome.
J Clin Rheumatol
October 2024
From the Rheumatology and Clinical Immunology Unit-ERN ReCONNET, Department of Clinical and Experimental Sciences, ASST Spedali Civili and University of Brescia, Brescia, Italy.
Article Synopsis
- * Pregnancy management must be personalized to reflect individual disease features and treatment options to reduce risks for both mother and fetus.
- * The review highlights the importance of discussing fertility, assisted reproductive techniques, and contraception alongside the management of these inflammatory conditions.
Ovarian reserve alteration in premenopausal women with systemic sclerosis.
Rheumatol Int
December 2024
Department of Obstetrics and Gynecology, University Hospital Tübingen, Calwerstrasse 7, 72076, Tübingen, Germany.
Anti-Muellerian hormone (AMH) is produced by the granulosa cells of ovarian follicles. It serves as a sensitive laboratory parameter for assessing ovarian reserve. A reduced ovarian reserve has been observed in patients with various autoimmune diseases.
View Article and Find Full Text PDFCarpal tunnel syndrome related to rheumatic disease (Review).
Exp Ther Med
October 2024
Faculty of Medicine, University of Medicine and Pharmacy 'Grigore T. Popa', Iași 700115, Romania.
Carpal tunnel syndrome (CTS) is the most commonly occurring type of entrapment neuropathy in the world. Several conditions may contribute to the development of CTS, such as obesity, repetitive wrist movements, pregnancy, genetic predisposition and rheumatoid arthritis (RA) inflammation. CTS is characterized by a wide range of pathophysiological factors, including increased pressure, mechanical trauma and ischemic damage to the median nerve that runs through the wrist tunnel.
View Article and Find Full Text PDFAssessment of fertility and sexual dysfunction in women with systemic sclerosis: a narrative review of the literature.
Clin Exp Rheumatol
August 2024
Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Objectives: The aim of this work is to review the existing literature regarding sexual and reproductive function of women affected by systemic sclerosis and to establish the impact of the disease on the gynaecological-obstetrical field.
Methods: A systematic search has been conducted by means of PubMed, Cochrane, Google Scholar, until January 2024 by the keywords ''systemic sclerosis'', ''fertility'', "sexual dysfunction" and "pregnancy".
Results: Sexual dysfunction has been described in most of the studies.
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