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Primary central nervous system vasculitis: A diagnostic and therapeutic challenge. A series of 7 patients.
Neurologia (Engl Ed)
June 2024
Departamento de Neurología, Hospital General Universitario de Castellón, Castellón de la Plana, Spain.
Introduction: Primary central nervous system vasculitis (PCNSV) is a rare disease affecting medium- and small-calibre blood vessels of the central nervous system.
Objective: The aim of this study was to analyse clinical findings and diagnostic aspects, with special attention to histopathological findings, as well as the treatments used and treatment response in patients diagnosed with PCNSV at our hospital.
Patients And Methods: We conducted a retrospective descriptive analysis of patients with a diagnosis of PCNSV at discharge from our centre and meeting the 1988 Calabrese criteria.
Case Report: Rare Acute Abdomen: Focal Nodular Hyperplasia With Spontaneous Rupture.
Front Oncol
July 2022
Department of Infectious Diseases, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Focal nodular hyperplasia (FNH) of the liver is a benign lesion characterized by hypertrophic nodules with central star-shaped fibrous scars. The etiology and pathogenesis of FNH are not completely understood. A 43-year-old man was hospitalized because of acute abdominal pain.
View Article and Find Full Text PDFDietary nitrate prevents progression of carotid subclinical atherosclerosis through blood pressure-independent mechanisms in patients with or at risk of type 2 diabetes mellitus.
Br J Clin Pharmacol
December 2021
Department of Clinical Pharmacology, King's College London British Heart Foundation Centre, School of Cardiovascular Medicine and Sciences, UK.
Aims: To test if 6 months' intervention with dietary nitrate and spironolactone could affect carotid subclinical atherosclerosis and stiffness, respectively, vs. placebo/doxazosin, to control for blood pressure (BP).
Methods: A subgroup of participants in our double-blind, randomized-controlled, factorial VaSera trial had carotid imaging.
Interventional treatment options in pseudoaneurysms: different techniques in different localizations.
Pol J Radiol
August 2019
Department of Radiology, Health Sciences University, Tepecik Educational and Research Hospital, Izmir, Turkey.
Article Synopsis
- * Conventional angiography remains the main method for diagnosing pseudoaneurysms, while noninvasive techniques like duplex Doppler ultrasonography, MR angiography, and CT angiography are also effective.
- * The article emphasizes how interventional radiology has become the preferred treatment method over traditional surgery, discussing various percutaneous and endovascular approaches based on specific patient conditions.
Differential inhibitory response to telcagepant on αCGRP induced vasorelaxation and intracellular Ca levels in the perfused and non-perfused isolated rat middle cerebral artery.
J Headache Pain
December 2017
Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden.
Background: Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators identified to date. The present study elucidates the differential interaction of CGRP, its receptor and the effect of the CGRP-receptor antagonist telcagepant on intracellular Ca -levels and tension in rat middle cerebral arteries (MCA) by pressurized arteriography, FURA-2/wire myography and immunohistochemistry.
Methods: A pressurized arteriograph system was used to evaluate changes in MCA tension when subjected to CGRP and/or telcagepant.
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