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Relationship of Iron Deficiency, Anemia and Combination of Iron Deficiency With Anemia With Severity of Manifestations of Chronic Heart Failure. Additional Analysis of the Study "Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (J-CHF-RF)".
Kardiologiia
November 2024
Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University, Moscow; Pirogov Russian National Research Medical University, Moscow.
Aim To evaluate the role of iron deficiency (ID) identified by various criteria, anemia, and the combination of ID and anemia in determining the severity of the clinical course of chronic heart failure (CHF) in a retrospective analysis of data from 498 patients who participated in the ID-CHF-RF Russian multicenter program.Material and methods ID was diagnosed by the following three criteria established by the European Society of Cardiology (ESC) and the Russian Society of Cardiology (RSC): 1) ferritin concentration <100 μg/l or ferritin concentration 100-299 μg/l in combination with a decreased transferrin saturation (TS) <20%; 2) ID criteria that showed a high sensitivity and specificity when compared with bone marrow morphology (BMM): TS ≤19.8% or serum iron (SI) ≤13 μmol/l; and 3) a composite index including a ferritin concentration <100 μg/l in combination with TS <20% and SI ≤13 μmol/l.
View Article and Find Full Text PDFElectrophysiological Phenotype-Genotype Study of Sustained Monomorphic Ventricular Tachycardia in Inherited, High Arrhythmic Risk, Left Ventricular Cardiomyopathy.
Circ Arrhythm Electrophysiol
December 2024
Instituto de Investigación Biosanitaria ibs.GRANADA and Virgen de las Nieves University Hospital, Cardiology Department, Granada, Spain (E.C.-B., F.J.B.-J., P.J.S.-M., M.M.-L., M.A.-L., R.M.-R., L.T.-S., J.J.-J.).
Background: Among inherited cardiomyopathies involving the left ventricle, whether dilated or not, certain genotypes carry a well-established arrhythmic risk, notably manifested as sustained monomorphic ventricular tachycardia (SMVT). Nonetheless, the precise localization and electrophysiological profile of this substrate remain undisclosed across different genotypes.
Methods: Patients diagnosed with cardiomyopathy and left ventricle involvement due to high-risk genetic variants and SMVT treated by electrophysiological study were recruited from 18 European/US centers.
Intramyocardial fatty infiltration lesion in sporadic inclusion body myositis: a case report.
Int J Cardiovasc Imaging
October 2024
Cardiovascular Department of Cardiology, Division of Cardiology, Lausanne University Hospital, CHUV, Rue du Bugnon 46, Lausanne, 1005, Switzerland.
Sporadic inclusion body myositis (sIBM), the most common inflammatory muscle disorder in adults over 50 years, is often misdiagnosed due to its gradual onset and its common but unspecific muscle weakness in older adults. Diagnosis relies on clinical, radiological, and pathological features. Cardiac involvement is rare, prompting this case description and a comprehensive literature analysis.
View Article and Find Full Text PDFCardiac amyloidosis and red flags: natural history and its impact in morbimortality.
Med Clin (Barc)
October 2024
Servicio de Cardiología, Hospital General Universitario de Ciudad Real, Ciudad Real, España; Facultad de Medicina de Ciudad Real, Universidad de Castilla-La Mancha, España; Instituto de Investigación Biomédica de Castilla-La Mancha (IDISCAM), Toledo, España.
Introduction And Objectives: Red flags (RF) are typical cardiac and extracardiac manifestations that may precede the definitive diagnosis of cardiac amiloidosis (CA) by several years, playing a pivotal role in the early diagnosis of the disease. The principal aim of the research was to determine the chronology of onset of RF throughout the natural history of CA as well as its prognostic influence.
Patients And Methods: Observational, retrospective inquiry of consecutive patients with a definitive diagnosis of CA in a terciary hospital centre in Ciudad Real (Spain) between February 2016 and December 2023.
Cardiovascular comorbidities in psoriatic arthritis: state of the art.
Ther Adv Musculoskelet Dis
September 2024
Centre for Rheumatic Diseases, King's College London, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK.
Article Synopsis
- * The review discusses the mechanisms behind cardiovascular risks in PsA, including inflammatory cytokines and immune dysregulation, while evaluating current risk assessment tools and suggesting innovative biomarkers for a more accurate risk profile.
- * Treatment for PsA must consider the balance between effectively managing arthritis symptoms and the potential risks to cardiovascular health, requiring a collaborative approach from various medical specialties to improve overall patient outcomes.
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