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Meningitis and neurosensory hypoacousia due to Rickettsia sp. in Peru: case report.
Rev Peru Med Exp Salud Publica
October 2024
Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
We present the case of a young female health worker, resident in a high Andean region of Peru, with recent exposure to farm animals and arthropods, who developed acute febrile undifferentiated syndrome, severe thrombocytopenia and pulmonary and abdominal extravasation. Subsequently, the patient developed meningitis and early onset bilateral neurosensorial hypoacusis and showed reactive serology to acute infection by Rickettsia sp. Epidemiological and clinical considerations in the differential diagnosis for early management are discussed.
View Article and Find Full Text PDFUsefulness of next-generation sequencing for laboratory diagnosis of rickettsiosis.
PLoS Negl Trop Dis
October 2024
Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
Article Synopsis
- - The study examined six patients diagnosed with various rickettsiosis infections using metagenomic next-generation sequencing (mNGS), which can be challenging for traditional laboratory diagnostics.
- - One patient with Japanese spotted fever was quickly diagnosed through mNGS, while two others with Rickettsia felis infections showed the bacterium in lung samples; both patients were immunocompromised due to cancer treatments.
- - Three additional patients, presenting with fever and eschar, had negative Weil-Felix test results, but mNGS confirmed the presence of Orientia tsutsugamushi, indicating scrub typhus; this highlights mNGS as a vital tool alongside serology for diagnosing rickettsiosis.
A Clinical Study of Rickettsial Fever and Factors Affecting Its Outcome.
Cureus
July 2024
Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND.
Introduction: Rickettsiae comprise a family of obligate intracellular short gram-negative coco-bacilli and are transmitted by insects, mites, fleas, louse, and tick vectors. Scrub typhus, north-Asian tick typhus, rickettsia pox, and boutonniere fevers are common in India and Asia. In the early phase of illness during the initial five days, all these are indistinguishable among themselves; also, they mimic any other self-limiting viral fever.
View Article and Find Full Text PDFJapanese spotted fever complicated with pleural effusion in Zhejiang province, China: a case report and literature review.
J Infect Dev Ctries
July 2024
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Introduction: Japanese spotted fever (JSF) mainly occurs in Japan; however, it has been increasingly reported in China. JSF is typically characterized by fever, rash, and eschar, in addition to non-specific symptoms. Yet, reports on the pulmonary indicators in JSF are limited.
View Article and Find Full Text PDFCo-circulation of Hantavirus, Pathogenic spp., and spp. in Rodents in the Wanzhou Section of the Three Gorges Reservoir Region, 2021-2023.
Vector Borne Zoonotic Dis
October 2024
Wanzhou District Center for Disease Control and Prevention, Chongqing, China.
Rodent is a reservoir of various zoonotic pathogens. Wanzhou section of the Three Gorges reservoir region (TGRR) is a superior habitat for rodents, and the situation of rodent-borne zoonotic pathogens in this region has not been surveyed in recent years. Rodents were night trapped with mousecage or mousetrap in urban and surrounding towns' indoor or outdoor areas of the Wanzhou section of the TGRR, and nucleic acid was extracted from their lung or a mixture of liver, spleen, and kidney.
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