Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Differential expression of plasma extracellular vesicles microRNAs and exploration of their association with bone metabolism in childhood trauma participants treated in a psychosomatic clinic.
Front Endocrinol (Lausanne)
March 2025
Medical Sociology and Psychobiology, University of Potsdam, Potsdam, Germany.
Introduction: Early life stress (ELS) impacts neurotransmitters and cell communication, potentially disrupting neurological and physiological processes. Recently, ELS has been implicated in impaired bone metabolism, with extracellular vesicles (EVs) and their cargo, microRNAs (miRNAs), might affecting this process. This research aimed to elucidate the association between childhood trauma, a specific form of ELS, and bone metabolism through studying miRNA in EVs within three steps: firstly, examining alterations of EV miRNAs between ELS and controls, secondly analyzing associations between altered EV miRNAs and bone markers, and thirdly exploring the target gene prediction and enrichment pathways of altered EV miRNAs.
View Article and Find Full Text PDFPatient Needs and Treatment Goals in Chronic Atopic Pruritus: Does Eczema Make a Difference?
Acta Derm Venereol
March 2025
Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Chronic pruritus (≥ 6 weeks) is a frequent symptom in atopic diseases, with phenotypes ranging from non-lesional skin to inflammatory diseases like atopic dermatitis. Data on patients' needs and treatment goals depending on the skin phenotype and disease burden are limited. This study aimed to analyse the impact of distinct phenotypes of chronic atopic pruritus on disease burden and treatment goals.
View Article and Find Full Text PDFA randomized controlled trial of environmental richness on gastrointestinal symptoms, salivary cortisol, and gut microbiota in early childhood.
Sci Rep
March 2025
Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, 980-8575, Miyagi, Japan.
Gastrointestinal (GI) symptoms are common and can affect children's social lives. This study investigated the effects of exposure to a rich natural environment on GI symptoms, salivary cortisol levels, salivary amylase levels, and the gut microbiota in young children. Children aged 5-6 years from four kindergartens in Japan were randomly assigned to two groups: a nature childcare group and a regular childcare group.
View Article and Find Full Text PDFAssociation between oxidative balance score and risk of postpartum depression in Iranian women: a prospective cohort study.
Sci Rep
March 2025
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, P.O Box 14155-6117, Tehran, Iran.
The oxidative balance score (OBS) serves as a comprehensive measure of exposures related to oxidative stress, considering both dietary antioxidants and lifestyle exposures. There is no evidence regarding the relation between OBS and postpartum depression (PPD). In this study, we aimed to determine the relationship between OBS during pregnancy and PPD.
View Article and Find Full Text PDFBeyond the itch: the complex interplay of immune, neurological, and psychological factors in chronic urticaria.
J Neuroinflammation
March 2025
College of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, 430061, China.
Chronic urticaria (CU) arises from a multifaceted interplay of immunological, neurological, and psychological components. Immune dysregulation, mediated through both immunoglobulin E (IgE)-dependent and IgE-independent pathways, plays a pivotal role in CU pathogenesis, involving key effector cells such as mast cells (MCs), basophils, and eosinophils. This dysregulation culminates in the release of histamine, prostaglandins, and other mediators, which precipitate pruritus.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!