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Procyanidin-crosslinked gradient silk fibroin composite nanofiber scaffold with sandwich structure for rotator cuff repair.
Biomater Adv
January 2025
Department of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Rd., Shanghai 200233, PR China. Electronic address:
Improving the regeneration of the tendon-bone interface (TBI) helps to decrease the risk of rotator cuff retears after repair surgeries. Unfortunately, the lack of inherent healing capacity of the TBI, insufficient mechanical properties, and abnormal and persistent inflammation during repair are the key factors leading to suboptimal healing of the rotator cuff. Therefore, a high-strength rotator cuff repair material capable of regulating the unbalanced immune response and enhancing the regeneration of the TBI is urgently needed.
View Article and Find Full Text PDFAdolescence Does Not Divert Sex Offending Adolescents of Color from Criminal Legal System Involvement.
Child Maltreat
January 2025
Evansville, IN, USA.
After the United States Civil War, during Reconstruction, Southern states targeted Black youth and men for incarceration and forced labor, often charging them with rape, spawning the Black male rapist myth. This study explores evidence of a Reconstruction-era ethos in present-day treatment of youth of color accused of sexual assault. Specifically, we examined effects of perpetrator age and race on legal outcomes in 382 alleged child sexual abuse cases.
View Article and Find Full Text PDFFracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age.
N Engl J Med
January 2025
From the Department of Medicine, University of Auckland, Auckland, New Zealand (M.J.B., Z.N., A.M., C.G., V.P., B.M., A.G., I.R.R., G.G., A.H.); the Department of Psychology, Stanford University, Stanford, CA (C.G.); and the Department of Radiology, Starship Hospital, Auckland, New Zealand (S.B.).
Background: Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate administration would prevent vertebral fractures in early postmenopausal women is unknown.
Methods: We conducted a 10-year, prospective, double-blind, randomized, placebo-controlled trial involving early postmenopausal women (50 to 60 years of age) with bone mineral density T scores lower than 0 and higher than -2.
Sex Differences in Natural History and Health Outcomes Among Individuals With Tic Disorders.
Neurology
February 2025
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Objectives: To analyze sex differences in outcomes in Tourette syndrome (TS) and Persistent Motor or Vocal tic disorders (PMVT) in the Tourette Association of America International Consortium for Genetics (TAAICG) dataset.
Methods: The relationship between sex and clinical measures was explored in 2,403 participants (N = 2,109 with TS; N = 294 with PMVT) from the TAAICG dataset using generalized estimating equation regression models, and adjusted for age and family relationships.
Results: Female (vs male) participants with TS (25.
Vaginal infiltration for relief of neuropathic pain after sacrospinous hysteropexy: First successful mid-term report.
Medwave
January 2025
Unidad de Ginecología, Hospital El Carmen Dr. Luis Valentín Ferrada, Santiago, Camino Rinconada 1202 Maipú, 9274443, Chile.
Female genital prolapse, especially apical prolapse, significantly affects women's health and quality of life. Sacrospinous hysteropexy is a widely used surgical procedure to address this condition, presenting few postoperative complications. However, one of the reported complications is neuropathic pain resulting from damage to the branches of the pudendal nerve.
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