Antioxidants (Basel)
September 2024
College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
The seeds of ginkgo biloba L (GB) have been widely used worldwide. This study investigated the bioefficacies of whole GB seed powder (WGP) retaining the full nutrients of ginkgo against aging, atherosclerosis, and fatigue. The experimental results indicated that WGP lowered brain monoamine oxidase and serum malondialdehyde levels, enhanced thymus/spleen indexes, and improved learning ability, and delayed aging in senescent mice.
View Article and Find Full Text PDFChem Biodivers
November 2024
Luzhou Branch of Sichuan Tobacco Company, Luzhou, 646000, P. R. China.
The aberrant activation of NLRP3 inflammasomes is intricately linked to various inflammatory diseases. In this study, we present the discovery and optimization of a series of NLRP3 inflammasome inhibitors based on the pterostilbene skeleton. All compounds underwent screening to evaluate their inhibitory effects on LPS/Nigericin-induced IL-1β secretion and anti-cellular pyroptosis.
View Article and Find Full Text PDFFront Vet Sci
June 2024
Institute of Veterinary Pathology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Introduction: Canine cutaneous histiocytoma (CCH) is a benign tumor frequently occurring in young dogs which is derived from Langerhans cells (LC). Distinguishing features of this tumor are its spontaneous regression following a rapid tumor growth. Impaired control of immune checkpoints during tumor development and progression is a widespread phenomenon which may result in an absent or ineffective immune response.
View Article and Find Full Text PDFJ Ethnopharmacol
October 2024
Skin Health and Cosmetic Development & Evaluation Laboratory, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China. Electronic address:
Biochem Biophys Res Commun
September 2024
Natural and Biomimetic Medicine Research Center, West China School of Medicine, West China Hospital, Sichuan University, China. Electronic address:
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