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Acute Myeloid Leukemia Presenting as Common Colds: An Uncommon Consideration.
Cureus
January 2024
Leukemia, Memorial Sloan Kettering Cancer Center, New York, USA.
Acute myeloid leukemia is the most common form of leukemia and can present with a wide variety of signs and symptoms. This article presents a case of a middle-aged male who presented with ongoing upper respiratory cold-like symptoms and was then found to be severely pancytopenic. A diagnosis of acute myeloid leukemia was made after a bone marrow biopsy, and the patient underwent induction chemotherapy.
View Article and Find Full Text PDFFatal low-dose methotrexate toxicity: A case report and literature review.
Dermatol Ther
December 2022
Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Methotrexate (MTX) is a chemotherapeutic agent that acts primarily by inhibiting the folic acid cycle. In addition to its application for treating malignancies, MTX is also used to treat chronic inflammatory diseases including psoriasis. Adverse effects have been reported even at low doses (up to 25 mg/week), and there is risk of toxicity in the form of myelosuppression, hepatotoxicity, or pulmonary fibrosis.
View Article and Find Full Text PDFMushroom poisoning: A proposed new clinical classification.
Toxicon
January 2019
Dept. for Clinical Toxicology at II, Med. Klinik, TU, München, Munich, Germany.
Article Synopsis
- - Mushroom poisoning is on the rise and existing classifications are outdated, missing new identified syndromes, which complicates diagnosis.
- - A review of literature since 1994 resulted in a new classification with six major groups of mushroom poisoning based on specific clinical features, causation, and symptoms.
- - The proposed groups include cytotoxic, neurotoxic, myotoxic, and metabolic poisoning, each with further subcategories outlining distinct symptoms and pathogens.
Pediatric patients with bicytopenia/pancytopenia: review of etiologies and clinico-hematological profile at a tertiary center.
Indian J Pathol Microbiol
June 2011
Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.
Background: The etiology of bicytopenia/pancytopenia varies widely in children, ranging from transient marrow viral suppression to marrow infiltration by fatal malignancy. Depending on the etiology, the clinical presentation can be with fever, pallor or infection. Knowing the exact etiology is important for specific treatment and prognostication.
View Article and Find Full Text PDFLeishmaniasis among organ transplant recipients.
Lancet Infect Dis
March 2008
Department of Clinical Sciences L Sacco, Section of Infectious Diseases and Immunopathology, University of Milan, Milan, Italy.
Leishmaniasis is a rarely reported disease among transplant recipients; however, the number of published cases has quadrupled since the beginning of the 1990s. Most cases have been observed in patients living in countries of the Mediterranean basin. Leishmaniasis is most commonly associated with kidney transplantation (77%), and cases are also recorded among patients undergoing liver, heart, lung, pancreas, and bone marrow transplantation.
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