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[Neurorehabilitation in Parkinson's disease : focus on physical therapy].
Rev Med Suisse
January 2025
Service de neurologie, Clinique bernoise Montana, 3963 Crans-Montana.
Parkinson's disease affects around 6 million people worldwide. It causes both motor and non-motor symptoms. Since there is no cure, medical treatment aims to improve patients' quality of life.
View Article and Find Full Text PDFComprehensive analysis of the prognostic, immunological, and diagnostic roles of SIRT1 in pan-cancer and its validation in KIRC.
Front Immunol
January 2025
School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Background: Disturbances in DNA damage repair may lead to cancer. SIRT1, an NAD+-dependent deacetylase, plays a crucial role in maintaining cellular homeostasis through the regulation of processes such as histone posttranslational modifications, DNA repair, and cellular metabolism. However, a comprehensive exploration of SIRT1's involvement in pan-cancer remains lacking.
View Article and Find Full Text PDFMultiscale Three-Dimensional Evaluation and Analysis of Murine Lung Vasculature From Macro- to Micro-Structural Level.
Pulm Circ
January 2025
Department of Imaging and Pathology, Biomedical MRI KU Leuven Leuven Belgium.
The pulmonary vasculature plays a pivotal role in the development and progress of chronic lung diseases. Due to limitations of conventional two-dimensional histological methods, the complexity and the detailed anatomy of the lung blood circulation might be overlooked. In this study, we demonstrate the practical use of optical serial block face imaging (SBFI), ex vivo microcomputed tomography (micro-CT), and nondestructive optical tomography for visualization and quantification of the pulmonary circulation's 3D architecture from macro- to micro-structural levels in murine lung samples.
View Article and Find Full Text PDFBioinformatic approach to explain how Mg from seawater may be incorporated into coral skeletons.
R Soc Open Sci
January 2025
Atmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa 275-8564, Japan.
Corals have been used as geochemical proxies since the 1970s, playing a prominent role in paleoceanography. However, it has not been well elucidated how aqueous ions sourced from seawater are transported and precipitated in coral skeletons. There are limited foundational methods to differentiate and quantify biogenic and abiogenic effects during skeletal formation.
View Article and Find Full Text PDFFactors influencing sport development among women with disabilities: a case study of a visually impaired Spanish Paralympic woman.
Front Sports Act Living
January 2025
'Fundación Sanitas' Chair for Inclusive Sport Studies (CEDI), Department of Health and Human Performance, AFIPE Research Group, Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, Madrid, Spain.
Introduction: Women with disabilities may experience particular difficulties in starting and developing in sport, also in the Paralympic context. Although a great deal of research has been conducted with high-performance athletes, relatively few studies have focused on athletes with disabilities, especially Paralympic women using person-first approaches. Thus, the main objective of this study is to understand, through the experience and opinion of a Paralympian female athlete, how these athletes reach their full potential, identifying the elements and initiatives that can influence (whether positively or negatively) their sporting trajectory and developmental milestones.
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