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Nephrotoxic effect of cypermethrin ameliorated by nanocurcumin through antioxidative mechanism.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, 45142, Jazan, Saudi Arabia.
Cypermethrin is a pyrethroid showing nephrotoxicity by generating ROS-impaired oxidative stress and changes in inflammatory and apoptotic markers. The harmful consequences are intended to be mitigated by the imbalance between oxidants and antioxidants. The anti-inflammatory and antioxidant possessions of nanocurcumin (NC) with improved bioavailability ameliorate Cyp toxicity in rat kidneys.
View Article and Find Full Text PDFRisks of anti- therapy and long-term therapy with antisecretory drugs.
World J Gastroenterol
January 2025
Department of Therapy, North Caucasus State Academy, Cherkessk 369000, Russia.
() infection has a protective effect on gastroesophageal reflux disease (GERD). Both of these diseases have a very high incidence and prevalence. As a result, GERD often recurs after anti- therapy.
View Article and Find Full Text PDFReactivity of Wet scCO toward Reservoir and Caprock Formations under Elevated Pressure and Temperature Conditions: Implications for CCS and CO-Based Geothermal Energy Extraction.
Energy Fuels
January 2025
Geothermal Energy and Geofluids Group, Institute of Geophysics, Department of Earth and Planetary Sciences, ETH Zurich, Zurich 8092, Switzerland.
Carbon capture and storage (CCS) and CO-based geothermal energy are promising technologies for reducing CO emissions and mitigating climate change. Safe implementation of these technologies requires an understanding of how CO interacts with fluids and rocks at depth, particularly under elevated pressure and temperature. While CO-bearing aqueous solutions in geological reservoirs have been extensively studied, the chemical behavior of water-bearing supercritical CO remains largely overlooked by academics and practitioners alike.
View Article and Find Full Text PDFDistribution of Tunisian beet wild relatives ( sp.) according to morphological characteristics and eco-geographical origin.
Heliyon
January 2025
Laboratory of Plant Protection, National Institute of Agronomic Research of Tunisia, University of Carthage, Rue Hedi Karray, 2049, El-Menzah, Tunisia.
subsp. (L.) Arcang.
View Article and Find Full Text PDFMetformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway.
Arch Endocrinol Metab
January 2025
Fuzhou First General Hospital Affiliated with Fujian Medical University Department of Endocrinology FuzhouFujian China Department of Endocrinology, Fuzhou First General Hospital Affiliated with Fujian Medical University, Fuzhou, Fujian, China.
Objective: Diabetic neuropathy (DN) is an important complication of diabetes mellitus. Autophagy is considered to be potentially involved in the regulation of DN. Metformin is broadly utilized in the first-line treatment of diabetes.
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