Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Phytochemical-based nanosystems: recent advances and emerging application in antiviral photodynamic therapy.
Nanomedicine (Lond)
January 2025
Clinical Laboratory Science Section, Institute of Medical Science Technology, Universiti Kuala Lumpur, Kajang, Selangor, Malaysia.
Phytochemicals are typically natural bioactive compounds or metabolites produced by plants. Phytochemical-loaded nanocarrier systems, designed to overcome bioavailability limitations and enhance therapeutic effects, have garnered significant attention in recent years. The coronavirus disease 2019 (COVID-19) pandemic has intensified interest in the therapeutic application of phytochemicals to combat viral infections.
View Article and Find Full Text PDFFluorescence lifetime imaging in drug delivery research.
Adv Drug Deliv Rev
January 2025
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997, Moscow, Russia; School of Mathematical and Physical Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW 2109, Australia; Research Center for Translational Medicine, Sirius University of Science and Technology, 354340, Sochi, Russia; National Research Ogarev Mordovia State University, Saransk, Mordovia Republic 430005, Russia.
Once an exotic add-on to fluorescence microscopy for life science research, fluorescence lifetime imaging (FLIm) has become a powerful and increasingly utilised technique owing to its self-calibration nature, which affords superior quantification over conventional steady-state fluorescence imaging. This review focuses on the state-of-the-art implementation of FLIm related to the formulation, release, dosage, and mechanism of action of drugs aimed for innovative diagnostics and therapy. Quantitative measurements using FLIm have appeared instrumental for encapsulated drug delivery design, pharmacokinetics and pharmacodynamics, pathological investigations, early disease diagnosis, and evaluation of therapeutic efficacy.
View Article and Find Full Text PDFNanoplastics in focus: Exploring interdisciplinary approaches and future directions.
NanoImpact
January 2025
Géosciences Rennes, CNRS/Université Rennes, 263 av. Général Leclerc, 35000 Rennes, France.
Nanoplastics (NPs) are gaining increasing attention due to their widespread distribution and potential environmental and biological impacts. Spanning a variety of ecosystems - from soils and rivers to oceans and polar ice - NPs interact with complex biological and geochemical processes, posing risks to organisms across multiple trophic levels. Despite their growing presence, understanding the behavior, transport, and toxicity of nanoplastics remains challenging due to their diverse physical and chemical properties as well as the heterogeneity of environmental matrices.
View Article and Find Full Text PDFPhilanthropic drug development: understanding its importance, mechanisms, and future prospects.
Drug Discov Today
January 2025
University Witten/Herdecke, 58455 Witten, Germany; DEBRA Research gGmbH, 80336 Munich, Germany; Knowledge House GmbH, 40213 Düsseldorf, Germany. Electronic address:
Philanthropic drug development (PDD) addresses gaps in traditional pharmaceutical innovation, particularly for rare and underserved diseases. Cost and timeline challenges discourage new investments, especially in niche therapeutic areas. Patient organizations (POs) are uniquely positioned to help to reduce development challenges by providing expertise, supporting early research, fostering collaborations, and driving patient-centered clinical trials.
View Article and Find Full Text PDFAdsorption of emerging pollutants utilizing chitosan derivatives: Recent advances and future perspective.
Int J Biol Macromol
January 2025
Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India; Chemical Engineering Department, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India. Electronic address:
Globalization resulted in technological advancement, and urban population growth. Consequently, pollution emerged as an imminent risk to the survival of all species on Earth. Consequently, on a worldwide basis, sustainability become a major issue for legislators.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!