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Association between exposure to pyrethroids and chlorpyrifos at age 5 years and IQ at age 7 years among children from the Odense Child Cohort, a prospective birth cohort study.
Environ Res
January 2025
Department of Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark; Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark; OPEN Patient Data Explorative Network, Odense, Denmark.
Background: Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following pyrethroids exposure exist, but few studies have examined the long-term effects of childhood exposure to chlorpyrifos and pyrethroids on IQ.
Objective: To investigate the prospective associations between pyrethroids and chlorpyrifos exposure at age 5 years and IQ scores assessed at age 7.
Enhancing Small-for-Gestational-Age Prediction: Multi-Country Validation of Nuchal Thickness, Estimated Fetal Weight, and Machine Learning Models.
Prenat Diagn
January 2025
Department of Artificial Intelligence, Faculty of Computer Science and Information Technology, Universiti Malaya, Kuala Lumpur, Malaysia.
Objective: The first objective is to develop a nuchal thickness reference chart. The second objective is to compare rule-based algorithms and machine learning models in predicting small-for-gestational-age infants.
Method: This retrospective study involved singleton pregnancies at University Malaya Medical Centre, Malaysia, developed a nuchal thickness chart and evaluated its predictive value for small-for-gestational-age using Malaysian and Singapore cohorts.
Seroprevalence of and Associated Risk Factors for Bovine Viral Diarrhea in Dairy Cattle in and Around Nekemte Town, East Wallaga, Oromiya Regional State, Ethiopia.
Biomed Res Int
January 2025
College of Agriculture and Veterinary Medicine, Jimma University, Jimma, Ethiopia.
Bovine viral diarrhea virus (BVDV) is an important pathogen affecting dairy cattle all over the world by causing significant economic losses due to reproductive and respiratory problems, immunosuppressive effects, increased risk of morbidity, and calf mortality. A cross-sectional study was conducted from February 2021 to August 2021 to determine the seroprevalence of bovine viral diarrhea (BVD) and identify risk factors associated with its occurrence in and around Nekemte Town of Ethiopia. Blood samples were collected from 305 dairy cattle of 41 herds by using cluster-sampling method.
View Article and Find Full Text PDFFetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects.
JB JS Open Access
January 2025
Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, Kentucky.
Background: Therapies for cartilage restoration are of great interest, but current options provide limited results. In salamanders, interzone (IZN) tissue can regenerate large joint lesions. The mammalian homolog to this tissue exists during fetal development and exhibits remarkable chondrogenesis in vitro.
View Article and Find Full Text PDFRevisiting the unobtrusive role of exogenous stem cells beyond neural circuits replacement in spinal cord injury repair.
Theranostics
January 2025
Department of biochemistry and molecular biology, College of Life Sciences, Central South University, Changsha, 410078, Hunan, China.
Stem cell transplantation is a promising strategy to establish neural relays in situ for spinal cord injury (SCI) repair. Recent research has reported short-term survival of exogenous cells, irrespective of immunosuppressive drugs (ISD), results in similar function recovery, though the mechanisms remain unclear. This study aims to validate this short-term repair effect and the potential mechanisms in large animals.
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