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With the rapid development of Internet of Things (IoT) technology, embedded devices in various computer vision scenarios can realize real-time target detection and recognition tasks, such as intelligent manufacturing, automatic driving, smart home, and so on. YOLOv8, as an advanced deep learning model in the field of target detection, has attracted much attention for its excellent detection speed, high precision, and multi-task processing capability. However, since IoT embedded devices typically own limited computing resources, direct deployment of YOLOv8 is a big challenge, especially for real-time detection tasks.

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Growth hormone-releasing hormone signaling and manifestations within the cardiovascular system.

Rev Endocr Metab Disord

January 2025

Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Biomedical Research Building, 1501 N.W. 10th Avenue, Room 908, Miami, FL, 33136, USA.

Growth hormone (GH)-releasing hormone (GHRH), a hypothalamic peptide initially characterized for its role in GH regulation, has gained increasing attention due to its GH-independent action on peripheral physiology, including that of the cardiovascular system. While its effects on the peripheral vasculature are still under investigation, GHRH and synthetic agonists have exhibited remarkable receptor-mediated cardioprotective properties in preclinical models. GHRH and its analogs enhance myocardial function by improving contractility, reducing oxidative stress, inflammation, and offsetting pathological remodeling.

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Qualitative Metascience: A Framework for Cultivating Healthier and More Translationally Impactful Neuroscience-Neuroethics Research Ecosystems.

AJOB Neurosci

January 2025

The Stanley Center for Psychiatric Research, The Broad Institute of MIT, McLean Hospital, Mass General Brigham, and Harvard.

Navigating the demands of translational research requires not only addressing scientific issues, but also managing conflicting sociopolitical, cultural, psychosocial, epistemic, and ethical relationships across diverse communities and academic disciplines. Data and analysis of intensive interviews on these phenomena with researchers are presented here, which led to the co-design of a larger, ongoing study in a neuropsychiatric research community. The results generated a set of hypotheses-particularly regarding conflicts and challenges at the neuroscience-neuroethics interface as experienced by neuroscientists-which have not been fully articulated or examined in the neuroethics literature.

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Background: Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by mutations in the or genes, leading to dysregulation of the mTOR pathway and multisystemic manifestations. Epilepsy is a common neurologic feature of TSC, frequently accompanied by neuropsychiatric comorbidities. Understanding the relationship between epilepsy severity, TSC-associated neuropsychiatric disorders (TAND), and cognitive outcomes is crucial for optimizing patient care.

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