Livedo reticularis is a common side effect of treatment with amantadine for Parkinson's disease. Investigation of 40 such patients suggests that the livedo is a physiological response provoked by depletion of catecholamine stores in peripheral nerve terminals.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796527PMC
http://dx.doi.org/10.1136/bmj.2.5762.627DOI Listing

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