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Assessing the relationship of recommended diarrhea case management practices with the nutritional status of children aged between 0 to 59.9 months.
Health Open Res
November 2023
School of Public Health, Faculty of Health and Medical Sciences., The University of Adelaide, Adelaide, South Australia, 5005, Australia.
Background: Paediatric diarrhoea and malnutrition have a bidirectional relationship, which in turn augments the presence of each other. The diarrhoeal diseases in children can be prevented by using (ORS) and . The relationship between paediatric diarrhoea treatment guidelines with the nutritional status is not yet investigated, and this study primarily aims to examine the relationship of recommended diarrhoea case management practices with paediatric undernutrition (wasting, stunting and underweight) among children aged between 0 to 59 months.
View Article and Find Full Text PDFEpidemiology and antimicrobial resistance rates for Shigella species in a resource-rich setting.
Pathology
February 2025
Department of Microbiology and Infectious Diseases, Concord Repatriation General Hospital, NSW Health, Concord, NSW, Australia; Department of Microbiology and Infectious Diseases, Concord Microbiology, NSW Health Pathology, Concord, NSW, Australia; Concord Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; Sydney Infectious Diseases Institute, University of Sydney, Sydney, NSW, Australia. Electronic address:
Article Synopsis
- - Shigellosis is a serious diarrheal illness that causes significant health issues globally, often leading to severe complications.
- - There is a rising concern about multidrug-resistant (MDR) and extensively drug-resistant (XDR) Shigella species, requiring ongoing monitoring of local resistance patterns to inform effective antibiotic treatment.
- - A study analyzing fecal samples from 2013 to 2023 shows a notable increase in resistance to important antibiotics like third-generation cephalosporins, azithromycin, and ciprofloxacin, as well as a rise in MDR and XDR strains.
Expression and purification of TolC as a recombinant protein vaccine against Shigella flexneri and evaluation of immunogenic response in mice.
Microb Pathog
March 2024
Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:
Background: Shigella is one of the major causes of dysenteric diarrhea, which is known shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global scale especially children less than 5 years old. No licensed vaccine is available against shigelosis, therefore, efforts for develop an effective and safe vaccine against Shigella as before needed.
View Article and Find Full Text PDFAntibiotic utilization pattern in treatment of acute diarrheal diseases: the case of Hiwot Fana Specialized University Hospital, Harar, Ethiopia.
J Pharm Policy Pract
May 2023
Pharmacology Department, School of Medicine, College of Medicine and Health Science, Dire Dawa University, Dire Dawa, Ethiopia.
Background: The vast majority of acute diarrheal diseases are self-limiting and do not require treatment on a regular basis. Empirical antibiotics should only be used to treat dysenteric and invasive bacterial diarrhea. Antibiotic misuse in the treatment of acute diarrhea is widespread in clinical practice worldwide.
View Article and Find Full Text PDFMucosal Immune Profiles Associated with Diarrheal Disease Severity in - and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study.
mBio
August 2022
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Enteropathogenic Escherichia coli (EPEC) and are etiologic agents of diarrhea in children <5 years old living in resource-poor countries. Repeated bouts of infection lead to lifelong morbidity and even death. The goal of this study was to characterize local mucosal immune responses in - and EPEC-infected children <5 years of age with moderate to severe diarrhea (MSD) enrolled in the Global Enteric Multicenter Study (GEMS).
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