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Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre.
Pediatr Surg Int
December 2024
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Purpose: Congenital diaphragmatic hernia (CDH) is associated with congenital heart disease (CHD) and index newborns reportedly may experience cardiac arrhythmia disorders [Tella et al.-Pediatric Critical Care Medicine 2022]. This study analyses, details and reports contemporary outcome metrics of CHD and cardiac rhythm disease (CRD) in CDH babies attending a university surgical centre.
View Article and Find Full Text PDFA Complex Presentation of Vestibular Paroxysmia in an Adolescent With Wolff- Parkinson-White Syndrome.
Pediatr Neurol
December 2024
Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts. Electronic address:
Article Synopsis
- Vestibular paroxysmia is a rare vestibular disorder caused by the compression or irritation of the eighth cranial nerve, which can be challenging to diagnose in children.
- A case study discusses a 16-year-old male who experienced episodes of vertigo and unsteadiness weeks after a COVID-19 infection, showing symptoms that included abrupt onset and no loss of consciousness.
- After testing negative for most conditions and struggling with various treatments, the patient's symptoms improved significantly with carbamazepine, highlighting the importance of timely diagnosis and treatment for better quality of life.
Echocardiographic Findings in Children of Patients Diagnosed with PRKAG2 Syndrome.
Arq Bras Cardiol
September 2024
Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, MG - Brasil.
Article Synopsis
- PRKAG2 syndrome often appears in teens and young adults, leading to serious heart issues and sudden death; early echocardiographic findings in children of affected parents could help in prevention and treatment.
- The study involved 7 children of diagnosed PRKAG2 syndrome patients, aged 9 months to 12 years, undergoing echocardiography, with results compared against 7 healthy controls.
- Results showed these children had significant increases in several echocardiographic measurements indicating early signs of potential heart issues, suggesting echocardiography could aid in early detection before symptoms show.
Dual challenge inside the womb: a case report of concomitant fetal atrio-ventricular block associated with maternal anti-SSA antibodies and fetal tachyarrhythmia diagnosed as Wolff-Parkinson-White syndrome after birth.
Front Immunol
August 2024
Rheumatology Department, Unidade Local de Saúde do Hospital de Santa Maria, Lisbon, Portugal.
Article Synopsis
- - Fetal autoimmune atrioventricular block (AVB) is a rare condition caused by maternal anti-SSA/Ro or Anti-SSB/La auto-antibodies affecting the fetal heart, leading to serious issues like inflammation and damage to the AV node.
- - A patient with a history of high antibody levels and hypothyroidism showed improvements in a first-degree AV block during pregnancy after treatment with dexamethasone and intravenous immunoglobulin.
- - The fetus later developed a tachyarrhythmia requiring medication, and after birth, was diagnosed with Wolff-Parkinson-White Syndrome (WPWS), marking the first known instance of AVB co-existing with WPWS.
A case of Williams syndrome with Wolff-Parkinson-White syndrome.
Birth Defects Res
July 2024
Department of Pediatric Genetics, Ege University School of Medicine, Izmir, Turkey.
Introduction: Williams syndrome (WS) cases have been reported to have with 25-100 times greater increased risk of sudden cardiac death (SCD). SCD has been reported in cases without any evidence of structural cardiovascular anomalies. Wolff-Parkinson-White (WPW) syndrome is characterized by short PR interval and delta wave.
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