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An evaluation of trends for mesothelioma mortality in American women: Addressing the content of a recent Morbidity and Mortality Weekly Report (MMWR).
Toxicol Ind Health
January 2025
Paustenbach and Associates, Jackson, WY, USA.
Mesothelioma is a fatal disease that has historically been associated with exposure to airborne asbestos. Because occupational asbestos exposures dropped dramatically in the late 1960s and early 1970s, far fewer cases of mesothelioma today are due to these fibers but, instead, are usually a result of the aging process or genetic predisposition. In May of 2022, a Morbidity and Mortality Weekly Report (MMWR) was issued by the Centers for Disease Control and Prevention (CDC) regarding malignant mesothelioma incidence in women from 1999 to 2020.
View Article and Find Full Text PDFBurden of malignant mesothelioma in China during 1990-2019 and the projections through 2029.
J Natl Cancer Cent
September 2024
Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, China.
Objective: To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.
Methods: Data on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DALYs) associated with MM among different age groups. Temporal trends during 1990-2019 were analyzed by the Joinpoint regression models using 95% confidence interval (CI), while the projections through 2029 were calculated by the Bayesian age-period-cohort model.
Assessing lifetime occupational chrysotile inhalation exposure, respiratory symptoms, and lung cancer risk among brake maintenance workers in Malaysia.
Toxicol Ind Health
November 2024
Consultation, Research and Development Department, National Institute of Occupational Safety and Health, Bandar Baru Bangi, Malaysia.
Article Synopsis
- * The cumulative exposure levels to chrysotile were measured, with most workers being young males, and the inhalation levels ranged widely, with a median exposure of 0.0018 f/mL.years.
- * Findings revealed a low prevalence of cough (11.7%) and an even lower lung cancer mortality risk (less than 1%), suggesting that the workers faced minimal cancer risks due to their lower exposure levels.*
The presence of erionite in North American geologies and the estimated mesothelioma potency by region.
Inhal Toxicol
March 2024
Paustenbach and Associates, Jackson, WY, USA.
Objective: Erionite is a naturally occurring fibrous mineral found in soils in some geographical regions. Known for its potency for causing mesothelioma in the Cappadocia region of Turkey, the erionite fiber has attracted interest in the United States due to its presence in a band of rock that extends from Mexico to Montana. There are few toxicology studies of erionite, but all show it to have unusually high chronic toxicity.
View Article and Find Full Text PDFLung fibre burden and risk of malignant mesothelioma in shipyard workers: a necropsy-based case-control study.
Ann Work Expo Health
June 2024
Formerly Mesothelioma Registry, Occupational Health Unit, Local Health Authority, viale Duca degli Abruzzi 15, 25124 Brescia, Italy.
Objectives: In Italy, the highest pleural cancer mortality and incidence have been observed among Italian regions where the 2 largest Italian shipyards were (and are) located. The objective of this study was to assess the exposure-response relationship for mesothelioma among male workers employed in the Monfalcone, Italy, shipyard.
Methods: We conducted a necropsy-based case-control study.
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