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Highly efficient removal of per- and polyfluoroalkyl substances by extrusion-regenerated aminated polyurethane sponges.
Water Res
January 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, China.
Per- and polyfluoroalkyl substances (PFAS) are a class of persistent organic compounds widely detected in the environments. Due to their chemical stability, physical adsorption has emerged as one of the most promising techniques for remediating PFAS-containing wastewater, while some newly synthesized functional absorbents in powder form suffer from separation issues. Inspired by mussel biology, we have successfully synthesized a porous spongy absorbent termed aminated polyurethane (PU-PDA-PANI) with over 99.
View Article and Find Full Text PDFLong non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury.
Stem Cell Res Ther
January 2025
Department of Neurosurgery, The First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, China.
Background: Closed head injury (CHI) provokes a prominent neuroinflammation that may lead to long-term health consequences. Microglia plays pivotal and complex roles in neuroinflammation-mediated neuronal insult and repair following CHI. We previously reported that induced neural stem cells (iNSCs) can block the effects of CXCL12/CXCR4 signaling on NF-κB activation in activated microglia by CXCR4 overexpression.
View Article and Find Full Text PDFHsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation.
Commun Biol
January 2025
Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University, Shijiazhuang, 050017, China.
Aberrant autophagy in vascular smooth muscle cells (VSMCs) is associated with the progression of vascular remodeling diseases caused by neointimal hyperplasia. Platelet-derived growth factor-BB (PDGF-BB)-induced vascular remodeling is accompanied by autophagy activation, however, the involvement of circular RNAs (circRNAs) remains unclear. Here, we show the role of PDGF-BB-regulated hsa_circ_0001304 (circ-1304) in neointimal hyperplasia and its potential involvement in VSMC autophagy, while also elucidating the potential mechanisms.
View Article and Find Full Text PDFSmall bowel obstruction after caesarean section: an unusual complication of surgical haemostatic agent.
BMJ Case Rep
January 2025
Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
An unusual case of small bowel obstruction (SBO) due to haemostatic gelatin sponge placed during caesarean delivery is presented. A primigravida in their 30s underwent caesarean delivery at 39 weeks, and developed symptoms of SBO from the second postoperative day. Given the worsening condition of the patient and increasing abdominal girth, CT of the abdomen and pelvis was done which revealed features of SBO.
View Article and Find Full Text PDFAugmented silver sulfadiazine nanostructured lipid carriers impregnated collagen sponge for promoting burn wound healing.
Int J Biol Macromol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, University of Sadat City, P.O. Box 32897, Menoufia, Egypt; Nanomedicine Laboratory, Faculty of Pharmacy, University of Sadat City, P.O. Box 32897, Sadat City, Egypt. Electronic address:
Silver sulfadiazine (SSD) is a widely used antibacterial agent for burn wound treatment owing to its capability in re-epithelialization and wound healing. However, due to its low solubility, the need for an effective drug delivery system is mandatory. This study aimed to optimize SSD nanostructured lipid-based carriers (NLCs), incorporated in a collagen sponge form as an innovative topical dosage form for effective burn wound treatment.
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