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Gastroduodenal tuberculosis (GD-TB) is exceptionally rare. The clinical manifestations of gastrointestinal TB are diverse and non-specific, which makes diagnosis difficult, leading to delayed diagnosis and high mortality. As a peer-reviewer of , I would like to share my opinion on the article published by this journal.

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Foregut tuberculosis: Too close but miles apart.

World J Clin Cases

November 2024

Department of Medicine, Section of Gastroenterology, Aga Khan University Hospital, Karachi 74800, Pakistan.

The worldwide burden of tuberculosis (TB) has increased and it can involve virtually any organ of the body. Intestinal TB accounts for about 2% of the cases of TB worldwide. The ileocecal region is the most commonly affected site, and the foregut is rarely involved.

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Interferon-gamma release assays as a tool for differential diagnosis of gastrointestinal tuberculosis.

World J Clin Cases

September 2024

Department of Immunology, Medical-diagnostic laboratory Ramus, Simitli 6000, Bulgaria.

In this editorial, we comment on an article published in a recent issue of the . There is a pressing need for reliable tools for diagnosing tuberculosis (TB) of the gastrointestinal tract. Despite advancements in the diagnosis and treatment, TB remains a global health challenge.

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A case report entitled "Primary gastroduodenal tuberculosis presenting as gastric outlet obstruction" recently published in the presented a rare cause of gastric outlet obstruction and highlighted the atypical manner in which gastrointestinal tuberculosis (TB) can present. The literature with regards to this rare pathology is limited to case reports and case series with the largest being published using data from between 2003 and 2013. However, since then the diagnostic tools available have significantly changed with more modern and increasingly accurate tests now available.

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Background: Mycobacterium tuberculosis (TB) is the causative agent of TB, a chronic granulomatous illness. This disease is prevalent in low-income countries, posing a significant global health challenge. Gastrointestinal TB is one of the three forms.

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