Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Clinicopathologic idiosyncrasies of nasopharyngeal cancer in a moderate-risk Mediterranean region.
Acta Otorhinolaryngol Ital
June 2017
Department of Otorhinolaryngology, University Hospital of Patras, Patras, Greece.
Cancer of the nasopharynx displays an unparalleled skewness of its epidemiologic, pathogenic and clinico-prognostic characteristics depending on the geographic location. Between the endemic and sporadic forms, which occur in Southeastern Asia and Northern America, respectively, intermediate incidence is noted around the Mediterranean. This study describes the patterns of the disease affecting the population of Western Greece.
View Article and Find Full Text PDFIncreased WNT6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patients.
Int J Clin Exp Pathol
December 2016
WNT proteins are a family of secreted, cysteine-rich proteins containing 19 members. Signaling through WNT proteins is reported to be involved in carcinogenesis and cancer progression of gastrointestinal tumors, such as gastric cancer and colon cancer. The expression status of WNT6 in ESCCs and their clinico-prognostic significances remain to be elucidated.
View Article and Find Full Text PDFObjectives: No study evaluated circulating chemokine (CXC motif) ligand (CXCL)9 in 'patients with mixed cryoglobulinaemia and hepatitis C virus chronic infection' (MC+HCV). We aimed to measure CXCL9, IFN-γ and TNF-α in a series of MC+HCV to correlate these parameters to different clinical phenotypes.
Methods: Serum CXCL9, IFN-γ and TNF-α were assayed in 54 MC+HCV, in 54 patients with HCV chronic infection (HCV+) and in 54 sex- and age-matched controls.
The presence of autoimmune thyroiditis in mixed cryoglobulinemia patients is associated with high levels of circulating interleukin-6, but not of tumor necrosis factor-alpha.
Clin Exp Rheumatol
August 2011
Department of Internal Medicine, University of Pisa, Italy.
Objectives: To our knowledge, no study has evaluated serum levels of interleukin-6 (IL-6), together with tumour necrosis factor-alpha (TNF-α), in a large series of patients with 'mixed cryoglobulinemia and HCV chronic infection' (MC+HCV) in relation to the presence of autoimmune thyroiditis (AT). The aims of the study were to evaluate serum levels of IL-6 in MC+HCV patients and to correlate this parameter with the presence of AT and with circulating levels of TNF-α.
Methods: Serum IL-6 and TNF-α were assayed in 41 MC+HCV patients, in 41 MC+HCV patients with autoimmune thyroiditis (MC+AT), in 41 sex- and age-matched controls, and 20 AT patients.
Clinico-prognostic value of D-type cyclins and p27 in laryngeal cancer patients: a review.
Acta Otorhinolaryngol Ital
April 2005
Department of Otorhinolaryngological and Ophthalmological Sciences, Fondazione IRCCS, Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Italy.
Despite recent improvements in surgical and radiation therapy, failures still occur in patients with laryngeal squamous cell carcinomas, which may have a very different clinical outcome even when their clinical and histopathological characteristics are similar. The apparent inadequacy of "traditional" prognostic factors in predicting the clinical evolution of laryngeal squamous cell carcinomas has led to attempts to develop additional markers capable of distinguishing patients with a good prognosis from those who are more likely to relapse. A number of studies have demonstrated a relationship between tumourigenesis and alterations in the expression of cyclins, cyclin-dependent kinases and cyclin-dependent kinase inhibitors, but the data regarding laryngeal squamous cell carcinomas are somewhat conflicting.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!