Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Successful of autologous hematopoietic stem cell mobilization with plerixafor combined with G-CSF in pediatric neuroblastoma patients, a single center experience.
Transfus Apher Sci
January 2025
Pediatric Cell and Gene Therapy Research Centre, Gene, Cell & Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: Neuroblastoma (NB) is the most common extracranial solid tumor in pediatric. In highrisk NB patients, the 5-year overall survival rate (OS) remains a stark < 50 % with conventional therapies. Autologous hematopoietic stem cell transplantation with high dose chemotherapies was used in poor prognosis and high-risk patients.
View Article and Find Full Text PDFLong-Term Outcomes and Quality of Life of High-Risk Neuroblastoma Patients Treated with a Multimodal Treatment Including Anti-GD2 Immunotherapy: A Retrospective Cohort Study.
Cancers (Basel)
January 2025
Department of Haematology and Oncology, University Children's Hospital, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany.
Background: The incorporation of anti-GD2 antibodies such as ch14.18/SP2/0 into the multimodal treatment of high-risk neuroblastoma (HR-NB) patients has improved their outcomes. As studies assessing the long-term outcomes, long-term sequelae, and health-related quality of life (HRQoL) of this treatment are limited, this retrospective analysis aimed to explore these.
View Article and Find Full Text PDFAntidepressant and anxiolytic effects of Wuling Capsule in CSDS mice: Alleviating HPA axis hyperactivity via the Nesfatin-1/NF-κB signaling pathway.
J Ethnopharmacol
February 2025
Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Institute of Acupuncture Research, Academy of Integrative Medicine, Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function, Shanghai Medical College, Fudan University, Shanghai, 200032, China. Electronic address:
Article Synopsis
- The Wuling capsule, a traditional Chinese medicine derived from Xylaria nigripes, is traditionally used to treat depression and anxiety, though its exact mechanisms are not fully understood.
- This study investigates how Wuling capsule alleviates depression and anxiety-like behaviors in mice subjected to chronic social defeat stress, utilizing various behavioral tests and biochemical analyses.
- Results show that the capsule contains 123 components, with Nesfatin-1 playing a key role; increased Nesfatin-1 levels are linked to depression symptoms, while reducing its expression can alleviate these effects.
Metanephrine mirage: distinguishing the phaeocopies, a case report and literature review.
Clin Diabetes Endocrinol
November 2024
Department of Endocrinology and Diabetes, Western Health, 176 Furlong Rd, St Albans, VIC, 3021, Australia.
Background: We present one of only seven reported cases of a catecholamine-secreting adrenal neuroblastoma in an adult. The case is used as a platform to discuss key biochemical, genomic and imaging considerations that are central to the successful, targeted management of catecholamine-secreting adrenal tumours.
Case Presentation: A 63-year-old male was urgently reviewed at a tertiary hospital endocrinology outpatient clinic for a 12 cm right-sided adrenal incidentaloma.
Robotic Surgery in Paediatric Oncology: Expanding Boundaries and Defining Relevant Indications.
J Pediatr Surg
October 2024
Department of Pediatric Surgery and Urology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Paris Cité, Paris, France.
Article Synopsis
- The article outlines the development and growth of the Multidisciplinary Paediatric Robotic Program at Hôpital Necker-Enfants Malades in Paris, emphasizing the importance of a safe environment for patients and staff throughout all surgical phases.
- It highlights how robotic surgery enhances the precision of operations on tumours, with careful consideration of tumour characteristics and surgical experience to determine feasibility.
- The program aims for excellent cancer outcomes using minimally invasive techniques, focusing on selected paediatric tumours such as endocrine, neuroblastic, and renal cancers, while anticipating the future integration of robotic and image-guided surgery.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!