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Associations between breastfeeding and breast cancer risk through mammographic breast density in a cohort of Korean women.
Int J Epidemiol
December 2024
Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
Background: Mammographic breast density has been suggested to play a role as a mediator between the risk factors for breast cancer (BC) and BC risk. We investigated the extent to which never breastfeeding is a risk factor for BC and how this risk is further mediated by increased mammographic breast density.
Methods: This retrospective cohort study included 4 136 723 women aged ≥40 years who underwent mammographic screening between 2009 and 2010 and were followed up until 31 December 2020.
Australian radiographers' digital era practice in selecting the image receptor angle for female body habitus for the mediolateral oblique view of the breast.
Radiography (Lond)
October 2024
School of Dentistry and Medical Sciences, Discipline of Medical Radiation Science Faculty of Science and Health Charles Sturt University, Locked Bag 588, Building 30, Boorooma Street Wagga, Wagga NSW 2678, Australia. Electronic address:
Introduction: Correct alignment of the image receptor (IR) in mammography for the mediolateral oblique (MLO) view of the breast is fundamental to enable the maximum inclusion of breast tissue. This study aims to assess Australian radiographers' knowledge and digital era practice in selecting the IR angle for female body habitus in the MLO view of the breast.
Methods: An online survey was distributed to all members of the Australian Society of Medical Imaging and Radiation Therapy (ASMIRT) through their electronic newsletter and via direct email to radiographers holding the Certificate of Mammographic Practice (CMP).
Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study.
Breast Cancer Res
September 2024
School of Population Health, RCSI University of Medicine and Health Sciences, Beaux Lane House, Mercer Street Lower, Dublin 2, Ireland.
Article Synopsis
- Elevated mammographic density (MD) is a significant risk factor for breast cancer, and this study investigates how factors like childbirth, age at first birth, and breastfeeding relate to MD in a large group of women across different countries.
- The research analyzed data from 11,755 women aged 35-85 years, focusing on how factors such as the number of births and the timing of the first birth influence measurements of MD.
- The findings suggest that having more children decreases MD, while older age at first birth is linked to higher MD, particularly in post-menopausal women, highlighting the complex relationships between reproductive factors and breast density.
Contrast-enhanced mammography for surveillance in women with a personal history of breast cancer.
Breast Cancer Res Treat
November 2024
The Royal Melbourne Hospital, Grattan Street, Parkville, Australia.
Purpose: Women with a personal history of breast cancer have an increased risk of subsequent breast malignancy and may benefit from more sensitive surveillance than conventional mammography (MG). We previously reported outcomes for first surveillance episode using contrast-enhanced mammography (CEM), demonstrating higher sensitivity and comparable specificity to MG. We now report CEM performance for subsequent surveillance.
View Article and Find Full Text PDFMammographic density mediates the protective effect of early-life body size on breast cancer risk.
Nat Commun
May 2024
University of Bristol, MRC Integrative Epidemiology Unit, Bristol, UK.
The unexplained protective effect of childhood adiposity on breast cancer risk may be mediated via mammographic density (MD). Here, we investigate a complex relationship between adiposity in childhood and adulthood, puberty onset, MD phenotypes (dense area (DA), non-dense area (NDA), percent density (PD)), and their effects on breast cancer. We use Mendelian randomization (MR) and multivariable MR to estimate the total and direct effects of adiposity and age at menarche on MD phenotypes.
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