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Third Trimester Stillbirth Associated With Hamartoma of Mature Cardiac Myocytes (HMCM).
Pediatr Dev Pathol
September 2024
BCNatal | Fetal Medicine Research Center (Hospital Clínic and Hospital Sant Joan de Déu), University of Barcelona, Barcelona, Spain.
Article Synopsis
- * The stillborn was 32 weeks gestation, and an autopsy revealed a structurally normal heart with a small nodule beneath the membranous septum.
- * The nodule, consisting of disorganized cardiac cells and mild fibrosis, was identified as a rare tumor called HMCM, highlighting the need to consider it in diagnosing fetal heart tumors.
Echocardiography-Guided Radiofrequency Ablation for Cardiac Tumors.
JACC CardioOncol
August 2024
Xijing Ultrasound Interventional Treatment Center for Cancer, Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Article Synopsis
- Patients with cardiac tumors often face difficulties with surgery due to their poor health, and a new procedure called TARFACT offers a less invasive way to provide palliative care.
- The study involved five patients with various types of cardiac tumors who underwent TARFACT, followed by comprehensive assessments through different medical tests.
- Results showed significant reductions in tumor size, improved heart function, and better overall health in most patients over a follow-up period, indicating TARFACT’s potential as a viable treatment option.
Additional value of cardiac magnetic resonance parametric mapping in tissue characterization of common benign paediatric cardiac tumours.
Eur Heart J Cardiovasc Imaging
December 2024
Advanced Cardiothoracic Imaging Unit and Multimodality Imaging Research Unit, Bambino Gesù Children's Hospital IRCSS, Rome, Italy.
Article Synopsis
- The study focuses on the use of Cardiac Magnetic Resonance (CMR) parametric mapping to better characterize pediatric cardiac tumors, an area that hasn't been thoroughly explored.
- In a sample of 16 pediatric patients, various tumors were identified, including hemangiomas, fibromas, rhabdomyomas, and lipomas, with significant differences found in native T1 and extracellular volume (ECV) values among these types.
- The findings suggest that mass mapping analysis is both feasible and reliable for children, with ECV values being particularly useful for differentiating tumor types, closely resembling normal heart tissue in rhabdomyoma, and showing distinct measurements in the other tumor types.*
Cardiac rhabdomyoma: an uncommon culprit in sudden infant death.
Forensic Sci Med Pathol
September 2024
Department of Pathology, St. Louis University School of Medicine, St. Louis, MO, USA.
Article Synopsis
- - Sudden infant death syndrome (SIDS) is a common but poorly understood cause of mortality in infants, with pediatric cardiac tumors possibly contributing to some cases.
- - Autopsies, including both gross and microscopic heart examinations, are vital to identifying hidden cardiac tumors like rhabdomyomas, which can lead to sudden death.
- - A case of a healthy 5-month-old infant appeared to be SIDS at first, but microscopic analysis revealed a cardiac rhabdomyoma that was missed during gross examination, highlighting the need for thorough microscopic analysis to avoid missed diagnoses.
Myocardial fatty foci on cardiac MRI in an adult with tuberous sclerosis complex.
Int J Cardiovasc Imaging
November 2024
The University of Texas Health Science Center at Houston, School of Public Health, 6410 Fannin Street, Suite 425, Houston, TX, 77030, USA.
Article Synopsis
- A 38-year-old woman with Tuberous Sclerosis Complex (TSC) showed cardiac MRI results, specifically regressed rhabdomyomas.
- The presence of myocardial fatty foci in such patients may indicate broader organ involvement, though this factor isn't included in TSC diagnostic guidelines.
- Careful analysis of abnormal first pass perfusion and late Gadolinium enhancement on MRI is crucial to prevent misdiagnosis in TSC patients.
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