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The results from the comparative clinical studies on the effectiveness of tetraolean and tetracycline are summed up about 1672 patients with acute and exacerbated infections of the respiratory organs (1036 patient, treated by ten teams, working on the theme given in advance "Comparative clinical studies between tetraolean and tetracyclin in acute pneumonia", 164 patients with postgrippe viral-bacterial pneumonia, treated during the grippe epidemy 1972/1973 and 445 patient treated at the Therapeutic Clinic, Sofia during 1967-1972). The total results reveal that, according to the adopted objective indices, the therapeutic effect of tetraolean is with a statistically significant superiority over tetracyclin. The beneficial results obtained in the treatment of 14 patients with endocarditis lenta are also reported.

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The results from the treatment of 1086 patients, treated at the Therapeutic Clinic, HMI- Sofia were followed up for the period 1961-1970 incld. Acute bacterial and vuris-bacterial pneumonias were found in 318 patients, 475 of the patients were with exacerbated chronic bronchitis and bronchiectasis, with exacerbated chronic pyelo-nephritis -216 patients and with exacerbated chronic cholecystitis and cholangiohepatitis --92 patients. The effect of the treatment was determined according to a three-stage scale "good" with complete clinical healing (in acute pneumonia), with "improvement"--with complete clinical remission (in chronic infections) and "without effect".

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[Clinical and biological aspects of chronic brucellosis].

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol

March 1976

The present study refers to 53 cases of chronic brucellosis admitted to the clinic or followed up in an out-patient unit for ten years (1962-1971). There was a total of 946 days in hospital and 1688 days of occupational disability, about 40% of the patients necessitating repeated hospitalization because of the relapsing course of the disease. This group of cases presented the classical dominant features of an occupational anthropozoonoses (90.

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