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Patient with composite haemangioendothelioma containing angiosarcoma-like areas in the setting of congenital lymphoedema mimicking Stewart-Treves syndrome: a case report.
Diagn Pathol
June 2023
Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Article Synopsis
- Composite haemangioendothelioma is a rare vascular tumor that can exhibit low to medium malignant potential and is diagnosed by identifying different vascular components through histopathology.
- A case study describes a 49-year-old man with chronic lymphoedema who developed this tumor, which showed high-grade angiosarcoma-like features but behaved less aggressively, confusing it with the more severe Stewart-Treves syndrome.
- Despite needing potentially extensive surgery (hemipelvectomy), the patient opted against it and, after two years of monitoring, experienced no disease progression, indicating the need for accurate diagnosis to avoid unnecessary procedures.
Clinicopathologic features of Stewart-Treves syndrome.
Int J Clin Exp Pathol
March 2019
Department of Pathology, Aviation General Hospital Beijing, China.
Aims: To demonstrate clinicopathologic features of Stewart-Treves syndrome (STS) including clinical manifestations, morphology, immunophenotype (especially c-MYC amplification), differential diagnosis, pathogenesis, treatment and prognosis.
Methods And Results: 17 cases of STS were retrospectively archived, involving 6 cases of postmastectomy, 3 cases of postoperative cervical cancer and 8 cases of chronic lymphatic obstruction without history of malignancy. Seven of 9 cancer patients had undergone radiotherapy.
Angiosarcoma arising from congenital primary lymphedema.
Pediatr Dermatol
November 2018
Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.
We herein report the case of a 3-year-old girl with atypical congenital right upper limb lymphedema who developed an angiosarcoma. Only a few cases have been reported following congenital form of lymphedema and only 4 in such a young child. We also summarize all cases of angiosarcoma associated with congenital lymphedema reported in the literature.
View Article and Find Full Text PDFA Supernumerary Nipple-Like Clinical Presentation of Lymphangioma Circumscriptum.
Case Rep Dermatol Med
February 2018
Department of Dermatology, University of Texas McGovern Medical School, Houston, TX, USA.
Lymphangioma circumscriptum is a superficially localized variant of lymphangioma. The characteristic clinical presentation is a "frogspawn" grouping of vesicles or papulovesicles on the proximal limb or limb girdle areas. Though most lymphangiomas develop congenitally, the lymphangioma circumscriptum subtype is known to present in adults.
View Article and Find Full Text PDFLymphangiosarcoma of the hip arising in a congenital non-irradiated lymphangioma.
J Dtsch Dermatol Ges
December 2017
Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
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