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Synergistic Anticandidal Effectiveness of Greenly Synthesized Zinc Oxide Nanoparticles with Antifungal Agents against Nosocomial Candidal Pathogens.
Microorganisms
July 2023
Botany and Microbiology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
The high prevalence of fungal resistance to antifungal drugs necessitates finding new antifungal combinations to boost the antifungal bioactivity of these agents. Hence, the aim of the present investigation was to greenly synthesize zinc oxide nanoparticles (ZnO-NPs) using an aqueous leaf extract of and investigate their antifungal activity and synergistic efficiency with common antifungal agents. The biofabricated ZnO-NPs were characterized to detect their physicochemical properties.
View Article and Find Full Text PDFDesign of a Transdermal Sustained Release Formulation Based on Water-Soluble Ointment Incorporating Tulobuterol Nanoparticles.
Pharmaceutics
November 2022
Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashiosaka 577-8502, Japan.
We aimed to investigate which base was suitable for preparing transdermal formulations incorporating tulobuterol (TUL) nanoparticles (30-180 nm) in this study. Three bases (water-soluble, absorptive, and aqueous ionic cream) were selected to prepare the transdermal formulations, and TUL nanoparticles were prepared with a bead-milling treatment. In the drug release study, the TUL release from the water-soluble ointment was higher than that from the other two ointments.
View Article and Find Full Text PDFAntibiotic Prophylaxis Prescribing Practice in Head and Neck Tumor Resection and Free Flap Reconstruction.
Open Forum Infect Dis
January 2022
Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Background: Adherence to guidelines for antibiotic prophylaxis is often poor and is an important target for antimicrobial stewardship programs. Prescribing audits that suggested poor adherence to guidelines in a plastic surgery department led to a targeted education program to bring antibiotic prescriptions in line with hospital guidelines. We reviewed whether this intervention was associated with changed perioperative prescribing and altered surgical outcomes, including the rate of surgical site infections, specifically looking at clean-contaminated head and neck tumor resections with free flap reconstruction.
View Article and Find Full Text PDFEvaluation of the effect of the gold nanoparticles prepared by green chemistry on the treatment of cutaneous candidiasis.
Curr Med Mycol
March 2021
Department of Basic Sciences, College of Dentistry, University of Kufa, Al-Najaf, Iraq.
Background And Purpose: Mineral nanoparticle synthesis via green chemistry is considered a novel procedure that has been introduced into some industries and medical fields. This paper aimed to focus on synthesized gold nanoparticles (AuNPs) prepared via green chemistry and their usage in the treatment of cutaneous candidiasis..
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