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Simultaneous monitoring of creatinine and urea in diversified clinical samples based on SERS-active PDMS-flower-like ZIF-67@Ag nanoparticles.
Anal Chim Acta
May 2025
Department of Nephrology, The First Affiliated Hospital of Ningbo University, Ningbo, 315010, Zhejiang, PR China. Electronic address:
The sensitive, efficient, and simultaneous assay of creatinine and urea in different body fluid is crucial for the daily detection and treatment of chronic kidney disease. Here, we exploited a versatile composite surface enhanced Raman scattering (SERS) substrate of polydimethylsiloxane (PDMS)-flower-like ZIF-67@Ag nanoparticles (NPs) based on simple in-situ growth and ion sputtering strategies. The plasmonic Ag NPs assembled on the three-dimensional anisotropic ZIF-67 matrix, facilitating numerous resonant electromagnetic "hotspots".
View Article and Find Full Text PDFA potential anti-Helicobacter pylori strategy: Exploring the antibacterial mechanism of organic acids in sea buckthorn (Hippophae rhamnoides L.).
Microbiol Res
March 2025
State Key Laboratory of Plateau Ecology and Agriculture, College of Agriculture and Animal Husbandry, Qinghai University, Xining 810016, China. Electronic address:
Helicobacter pylori (H. pylori) infection is a highly prevalent causative agent of various gastric diseases. The search for natural alternatives to antibiotics that can effectively inhibit H.
View Article and Find Full Text PDFComputational Identification of Potential Organocatalysts (CIPOC) Reveals a 2-aminoDMAP/Urea Catalyst Superior to Its Thiourea Analogue.
J Am Chem Soc
March 2025
Department of Chemistry, Middle East Technical University, 06800 Ankara, Türkiye.
Asymmetric organocatalysis by bifunctional acid- and base-type small organic molecules has emerged as a promising way to enhance stereoselective organic transformations since the beginning of this millennium. Takemoto's -amine/thiourea catalyst, an archetype in these endeavors, has encouraged many to design new multifunctional alternatives. However, the discovery of efficient catalysts in a library of thousands of candidates containing the desired functionalities in their structures remains a great challenge both synthetically and computationally.
View Article and Find Full Text PDFImpact of urea-molasses treated wheat straw levels in total mixed rations on growth and nutrient digestibility in Azikheli buffalo calves.
Trop Anim Health Prod
March 2025
Department of Veterinary Medical Sciences (DIMEVET), Alma Mater Studiorum - University of Bologna, Ozzano Dell'Emilia, Bologna, Italy.
This study investigates the impact of urea molasses-treated wheat straw on growth performance and nutrient digestibility in Azikheli buffalo male calves. A longitudinal experiment was conducted on sixteen calves, randomly assigned to four experimental dietary treatments (n = 4 per group). The experimental diets included a control group (U0) with untreated wheat straw and three groups where urea molasses-treated wheat straw replaced 33% (U33), 66% (U66), or 100% (U100) of the straw in the total mixed ration.
View Article and Find Full Text PDFEffects of Lactobacillus curvatus SQ-425 and Staphylococcus simulans 65-4 as starter cultures on sensory characteristics, microbial communities and metabolites in fermented sausage.
Food Res Int
April 2025
College of Life Science, South-Central MinZu University, Wuhan, Hubei 430074, China. Electronic address:
Mixed starting cultures have been reported to perform better than commonly used single Lactic acid bacteria in meat fermentation. Lactobacillus curvatus SQ-425 and Staphylococcus simulans 65-4 were screened from 67 sausages collected from southwest regions in China to investigate the effects of single and combined inoculation (SF and CMF) on sausages quality, while natural fermentation (NF) was used as a control group. Inoculation of mixed cultures resulted in a continuous decrease in pH during fermentation, an increase in redness values of sausages and the highest sensory score.
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